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2002-03 AFPE Gateway Research Scholarship Winners

VLADISLAV M. ABRAMOFF
St. John’s University College of Pharmacy and Allied Health Professions
Major: Pharmacy
GPA: 3.64/4.00
Expected Graduation: May 2004
Focus of Research: Investigation of the role of heavy metals, such as arsenic, cadmium, mercury, and nickel, in the development of mutations and cytotoxicity in human mammary epithelial cells. Results will lead to a better understanding of the contribution of metals, normally found in the environment, to human breast cancer.
Title of Research: “Cellular and Molecular Toxicity in Human Mammary Glands.”
Degrees Received: N/A
Honors Received: 2002, Rho Chi Pharmacy Honor Society; 2001, Hias Scholar; 2001, Rose Biller Scholar; 2001, Frolich Scholar; 2000, B. Burke Giblim Scholar; 2000, Golden Key International Honor Society; 2000, Ronald E. McNair Scholar; 1999- Present, Dean’s List
AFPE Award: BRISTOL-MYERS SQUIBB-AFPE Gateway Research Scholarship

RIZITA AKBARIYAZDI
The State University of New York at Buffalo School of Pharmacy and Pharmaceutical Sciences
Major: Pharm.D.
GPA: 3.93/4.00
Expected Graduation: June 2005
Focus of Research: There is no accepted method of measuring the response of MS patients to interferon-beta therapy. The focus of this project is to develop real time polymerase chain reaction assay for two genes induced by interferon-beta treatment.
Title of Research: “Molecular Markers for Measuring Interferon Treatment Responsiveness in Multiple Sclerosis. ”
Degrees Received: B.S., Chemistry and Biochemistry, University of Western Ontario, 2001
Honors Received: 2001, National Scholars Honor Society; 2001, Dean’s Honor List; 2000, Dean’s Honor List; American Society of Consultant Pharmacists (ASCP); PAWNY; CAPSI
AFPE Award: AAPS-AFPE Gateway Research Scholarship

JENNIFER BLAIR
University of New England College of Osteopathic Medicine
Major: Biochemistry
GPA: 3.92/4.00
Expected Graduation: May 2003
Focus of Research: To look at basal signaling at the mu opioid receptor and its role in opioid addiction, tolerance, and physical dependence. The research hypothesis is that neutral antagonists will precipitate a less severe withdrawal in opioid dependent animals.
Title of Research: “Role of Basal Signaling at the MU Opioid Receptor in Opioid Addiction, Tolerance, and Physical Dependence. ”
Degrees Received: N/A
Honors Received: 2002, Junior Academic Excellence; 2002, Phi Sigma Biology Honor Society; 1999-2001, Dean’s List; 2000-2001, Dean’s Scholarship; 2000-2001, Nomination Sophomore Academic Excellence; 1999-2000, CRC Freshman Chemistry Achievement Award
AFPE Award: AAPS-AFPE Gateway Research Scholarship

JENNIFER FEIG
Long Island University Arnold & Marie Schwartz College of Pharmacy and Health Sciences
Major: Pharmacy
GPA: 4.00/4.00
Expected Graduation: May 2004
Focus of Research: To identify the structural features that render a molecule a good surfactant and to determine the role that surface activity plays in the lipid-plasma DNA interaction. This will help to understand some of the underlying mechanisms of DNA transfer into the cells.
Title of Research: “Effect of Surface Tension on the Transfection Activity of Novel Cationic Reagents. ”
Degrees Received: N/A
Honors Received: 2002, Rosa Johnson Scholarship; 2002, Rho Chi Pharmacy Honor Society; 2002, Phi Lambda Sigma Pharmacy Honor Society; 2002, President of ASHP Chapter; 2001-2002, Patient Counseling Competition Winner; 2001-2002, Dean’s Award; 2000-2002, Dean’s List
AFPE Award: JOHNSON & JOHNSON-AFPE Gateway Research Scholarship

BRUCE R. HOFFMAN
University of Houston College of Pharmacy
Major: Pharmacy
GPA: 3.72/4.00
Expected Graduation: May 2004
Focus of Research: Dried samples of ten medicinal plants used topically by traditional herbalists have been collected in Ghana West Africa. Extractions of these samples will be made and screened both for their possible common chemical constituents and their antimicrobial activity.
Title of Research: “Antimicrobial Activities of Ten Medicinal Plants from Ghana.”
Degrees Received: M.S., Physics, The University of Texas, August 1994 (with honors)
B.S., Electrical Engineering, The University of Texas, May 1994 (with honors)
B.S., Anthropology, Michigan State University, June 1985
Honors Received: 2001, SSHP & ASP (President of UofH SSHP Chapter 2002-2003); 2000-2001, Dean’s Scholarship; 2000-2001, UofH Dean’s List; 2000, North Harris College (NHC) Honors College Scholarship; 2000, NHC Honor’s & Biology; 2000, Rising Star Awards; 1990, Member of Physics National Honors Society
AFPE Award: NACDS-AFPE Gateway Research Scholarship

GILBERT R. KINSEY
Medical University of South Carolina College of Pharmacy
Major: Pharm.D.
GPA: 3.50/4.00
Expected Graduation: May 2004
Focus of Research: Dr. Schnellermann’s lab has recently determined that 50% of cisplatin induced renal proximal tubule cellular (RPTC) apoptosis is caspace independent. The focus of this research is to 1. determine whether other DNA alkylating drugs produce caspace-independent RPTC apoptosis, 2. determine whether non-DNA alkylating drugs produce caspace-independent RPTC and 3. determine whether DNA alkylating drugs produce caspace independent RPTC apoptosis.
Title of Research: “Identification of Novel Apoptosis Pathways in Epithelial and Cancer Cells.”
Degrees Received: A.S., Science, Trident Technical College, June 2000
Honors Received: 2002, President Kappa Psi Pharmacy Fraternity (Iota Chapter); 2001, Kappa Psi Pharmacy Fraternity; 2001, ASP-APhA
AFPE Award: McKESSON-AFPE Gateway Research Scholarship

SHAHRZAD MOVAFAGH
University of California – San Francisco School of Pharmacy
Major: Pharmacy
GPA: 3.20/4.00
Expected Graduation: June 2003
Focus of Research: To characterize the role of different serotonin receptor subtypes in mediating the pharmacological effects of antipsychotics. In our experiments, we will measure dopamine, serotonin, and glutamate levels both in basal conditions and after acute or chronic administration of antipsychotic drugs using in-vivo microdialysis in freely moving mice.
Title of Research: “Contribution of Different Serotonin Receptor Subtypes to Antipsychotic Drug Action.”
Degrees Received: B.S., Psychology/Pre-Med, University of Maryland, May 1998
Honors Received: 1998-1999, NIH Research Fellowship; 1996, Golden Key National Honor Society
AFPE Award: ORTHO BIOTECH-AFPE Gateway Research Scholarship

PHUONG D. NGUYEN
University of Kansas School of Pharmacy
Major: Pharmacy
GPA: 3.69/4.00
Expected Graduation: May 2003
Focus of Research: To express and purify the EC2 and EC3 domains of E-cadherin for studying the mechanisms of E-cadherin interactions. E-cadherin is the protein that forms a “zipper” between cells. Thus, understanding this mechanism will allow us to modulate the intercellular junctions for enhancing drug delivery.
Title of Research: “Understanding the Formation of Intercellular Junctions by E-cadherin Interactions, Expression and Purification of EC-2 and EC-3 Domains.”
Degrees Received: B.S., Chemistry, Wichita State University, May 1997
Honors Received: 2001, PhRMA Research Fellowship; 2001, Rho Chi Pharmacy Honor Society; 2000, Merck Undergraduate Research Fellowship; 1999-2001, Dean’s Honor Rolls-Pharmacy; 1999-2001, Pharmacy Scholarship; 1994-1996, Dean’s Honor Rolls- Wichita State University; 1994, Kansas Outstanding Learner Award; 1993-1996, Bank IV Scholarship
AFPE Award: AAPS-AFPE Gateway Research Scholarship

WOO-HAENG PARK
Massachusetts College of Pharmacy and Health Sciences
Major: Pharmacy
GPA: 3.65/4.00
Expected Graduation: June 2003
Focus of Research: The long-term objective of this research is the development of new and more effective therapeutic agents for the treatment of breast cancer. The specific aims of this project are the design, synthesis, and characterization of a novel estradiol
Title of Research: “Design and Synthesis of a Novel Estrogen Antagonist.”
Degrees Received: B.S., Chemistry, University of Wisconsin-Madison, May 1999
Honors Received: N/A
AFPE Award: WYETH PHARMACEUTICALS-AFPE Gateway Research Scholarship

ELIZABETH A. RAYBON
The State University of New York at Buffalo School of Pharmacy and Pharmaceutical Sciences
Major: Pharmacy
GPA: 3.43/4.00
Expected Graduation: May 2004
Focus of Research: The research will focus on two dietary components, sulforaphane and phenethylisothiocyanate. We will identify the effect of treatment on gene expression in breast cancer and normal mammary cells. Time- and concentration-dependent effects of treatment will be examined.
Title of Research: “Effect of Treatment with the Dietary Components Sulforaphane and Phenethylisothiocyanate on Gene Expression in Human Mammary and Breast Cancer Cells.”
Degrees Received: B.A., Psychology, The State University of New York at Buffalo, 2001
B.A., Biology, Buffalo State College, 1997
Honors Received: 2002, Phi Lambda Sigma Pharmacy Honor Society; 2001, Academic Scholarship Award; 1997, CBS Inc. Academic Scholarship Award
AFPE Award: ASTRAZENECA-AFPE Gateway Research Scholarship

VERNON A. RAYFORD
University of Mississippi School of Pharmacy
Major: Pharmacy
GPA: 3.74/4.00
Expected Graduation: May 2003
Focus of Research: To obtain compounds with a relatively broad spectrum of activity against several major fungal pathogens. Because of sampangine’s present activity, it will be modified to increase in vivo activity.
Title of Research: “Development of New Sampangine Analogs with High Fungal In Vitro and In Vivo Activity.”
Degrees Received: N/A
Honors Received: 2001, Barry M. Goldwater Scholarship; 2001, Golden Key National Honor Society; 2000, National Society of Collegiate Scholars; 1999, McDonnell-Barksdale Honors College; 1999, Harold Parker Memorial Scholarship; 1999, F.A.P. Barnard Scholarship
AFPE Award: PFIZER-AFPE Gateway Research Scholarship

VERONICA I. RIERA
Southwestern Oklahoma State University School of Pharmacy
Major: Pharm.D.
GPA: 3.40/4.00
Expected Graduation: May 2004
Focus of Research: Extraction and quantification of glycyrrhizin from multiple licorice products to determine the variability of glycyrrhizin content as compared to product labeling.
Title of Research: “Variation of Glycyrrhizin Content in Licorice Dietary Supplement Products.”
Degrees Received: N/A
Honors Received: 2002, Southwestern Oklahoma State University Continuing Student Tuition Waiver; 2002, Phi Lambda Sigma Pharmacy Honor Society; 2002-2001, Oklahoma Hispanic Professional Association Scholarship; 2002-2001, Charles and Elizabeth Schultz Memorial Scholarship; 2002-2001, Glenna Kobel Memorial Scholarship; 2001, American Society of Health-System Pharmacists; 2000, American Chemical Society
AFPE Award: GLAXOSMITHKLINE-AFPE Gateway Research Scholarship

TAK SUM
South Dakota State University College of Pharmacy
Major: Pharmacy
GPA: 3.86/4.00
Expected Graduation: May 2005
Focus of Research: In this project, the effect of soy extract and the soy isoflavone genistein will be evaluated in the human cortical neuronal cell line HCNIA. This study will enable us to determine the neuro-protective effect of soy and soy phytochemicals.
Title of Research: “Effect of Soy Phytochemicals in Human Cortical Cells.”
Degrees Received: B.S., Chemistry, Minnesota State University-Mankato, May 2000
A.A., Arts, Bethany Lutheran College, May 1997
Honors Received: 2002, Lloyd Daniels & Helen Daniels; 2002,Bader Scholarships in Pharmacy; 2002, Rho Chi Award of Academic Excellence; 2002, Kappa Psi Pharmaceutical Fraternity; 2001, Dean’s List (SDSU); 1998, Chemistry Dept. Research Award; 1997-2000, Dean’s List- Minnesota State U.; 1998-2000, Ford Memorial Scholarship; 1995-1997, Dean’s List, Bethany Lutheran College; 1996-1997, Bethany Scholarship
AFPE Award: SANOFI-SYNTHELABO-AFPE Gateway Research Scholarship

BANI TAMRAZ
University of California – San Francisco School of Pharmacy
Major: Pharmacy
GPA: 2.97/4.00
Expected Graduation: June 2003
Focus of Research: To determine the correlation between infectivity of HIV-1 of CD4+ T-cells and their P-gp expression level using peripheral blood mononuclear cells obtained from healthy volunteers before and after induction of P-glycoprotein by oral administration. In addition, MDR1 genotypes in these cells will be evaluated as a further covariate.
Title of Research: “Significance of P-Glycoprotein on HIV Infectivity Under Induction Conditions.”
Degrees Received: B.S., Chemistry, University of California-Davis, June 1999
Honors Received: 1998, MURALS Participant Research Scholarship; 1998, SURPRISE Student Research Scholarship; 1998, Dow Chemical Scholarship; 1996, Davis Rotary Club Scholarship; 1995 & 1997-1998, Dean’s Honor List
AFPE Award: AAPS-AFPE Gateway Research Scholarship

NANCY M. WALTERS
Ohio Northern University College of Pharmacy
Major: Pharmacy
GPA: 3.43/4.00
Expected Graduation: May 2003
Focus of Research: The long-term goal of the research in our laboratory is to elucidate the role of dopamine (DA) in the selective serotonergic neurotoxicity induced by 3,4-methylendioxymethamphetamine (MDMA, “Ecstasy”). Numerous studies have suggested a putative role for DA in the neurotoxicity induced by MDMA. This proposal theorizes that the deamination of DA by monoamine oxidase-B (MAO-B) is responsible for the serotonergic neurotoxicity.
Title of Research: “Role of Excessive Dopamine Metabolism by MAO-B in the Selective Serotonergic Neurotoxicity Induced by 3,4-methylenedioxymethamphetamine (MDMA, Ecstasy).”
Degrees Received: N/A
Honors Received: 2000, Phi Eta Sigma, Alpha Lambda Delta CPFI, OSHP & ASP; 1998, Salutarian; 1998, Tandy Technology Scholar; 1998, J.A. Top Sales/Scholarship
AFPE Award: AAPS-AFPE Gateway Research Scholarship

SIUYANAMY YEUNG
The State University of New York at Buffalo School of Pharmacy and Pharmaceutical Sciences
Major: Pharmacy
GPA: 3.90/4.00
Expected Graduation: May 2005
Focus of Research: The research focuses on approaches to manage gamma-hydroxybutyric acid (GHB) toxicity. GHB is a drug of abuse used for its sedative and euphoriant properties. Studies will evaluate the effect of dose on the toxicokinetics and renal clearance of GHB in rats to identify approaches to increasing the clearance of GHB.
Title of Research: “Role of Excessive Dopamine Metabolism by MAO-B in the Selective Serotonergic Neurotoxicity Induced by 3,4-methylenedioxymethamphetamine (MDMA, Ecstasy).”
Degrees Received: N/A
Honors Received: 2001, Dean’s List Fall; 2001, Grace Capen Academic Award; 2001, Outstanding Achievement in Organic Chemistry; 2000, National Dean’s List; 2000, CRC Award for Achievement in Freshman Chemistry
AFPE Award: AAPS-AFPE Gateway Research Scholarship

ELIZABETH ZHONG
University of Illinois at Chicago College of Pharmacy
Major: Pharm.D.
GPA: 5.00/5.00
Expected Graduation: May 2003
Focus of Research: This research focuses on elucidating the impact of human genotype on patient’s pharmacoresponse. Specifically, this research assesses the impact of the CPIIIa P1A1/A2 polymorphism on aspirin’s effectiveness in preventing recurrent vascular events after an ischemic stroke. This will be done by comparing GPIIIa P1A1/A2 genotype and allele frequencies between 50 aspirin responders and 25 aspirin non-responders.
Title of Research: “Glycoprotein IIIa Genotype and Aspirin Research in Stroke.”
Degrees Received: N/A
Honors Received: 2002, Phi Kappa Phi; 2000-2002, High Honor; 2001, I. B. Crystal Memorial Award; 2001, Rho Chi Pharmacy Honor Society
AFPE Award: SCHERING-PLOUGH-AFPE Gateway Research Scholarship

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