MELINA Z. BAYRAMYAN
University of Southern California School of Pharmacy
|
| Major: |
Pharmaceutical Sciences |
| GPA: |
3.90/4.00 |
| Expected
Graduation: |
May 2005 |
| Focus
of Research: |
The purpose of this study is to develop a new computational SELEX
method to enhance the process of aptamer discovery. This involves
the development of a computer algorithm for the generation of nucleic
acid structure which will be extended to study of RNA-protein and
biomolecular conformational transitions. |
| Title
of Dissertation: |
“In Silico Aptamer Design: Computational SELEX” |
| Degrees
Received: |
Pharm.D., Pharmacy, University of Southern California, May 2000
|
| Honors
Received: |
2003, Outstanding Teaching Assistant; 2002, AFPE Pre-Doctoral Fellowship;
2002, USC Representative at GPEN; 2000, Organization of Istanbul Armenian
Scholarship; 1999, International Pharmacy Internship, OU Australia;
1998, Research Fellowship, USC School of Pharmacy; 1997-1999, Margaret
and John Blee Fellowship, USC; 1997, Dean’s Honor List, USC;
1995, Award from College Women’s Club of Pasadena; 1995-1993,
Dean’s Honor List, Glendale Community College; 1995-1993, The
National Dean’s List |
| AFPE
Award: |
JOSIAH KIRBY LILLY SR. Memorial Fellowship in the Pharmaceutical
Sciences |
|
LUKE BI
University of Minnesota College of Pharmacy
|
| Major: |
Pharmaceutics |
| GPA: |
3.71/4.00 |
| Expected
Graduation: |
May 2005 |
| Focus
of Research: |
To investigate the effect of drug pre-exposure on tacrine’s
first-pass metabolism and its oral bioavailability. To investigate
the extent of gut wall metabolism and its effect on oral bioavailability
of tacrine. |
| Title
of Dissertation: |
“Investigation of the Mechanism of the Nonlinear
Oral Delivery of Tacrine and its Hydroxylated Metabolites in Humans” |
| Degrees
Received: |
M.S., Chemistry, Southern Illinois University at Carbondale, May
1992
B.S., Inorganic Material Science, East China University of Chemical
Technology, July 1985 |
| Honors
Received: |
1987, 1st Prize of Scientific Achievement from Chinese EPA |
| AFPE
Award: |
|
|
ERICA L. BRADSHAW
University of Colorado Health Sciences Center School of Pharmacy
|
| Major: |
Pharmaceutical Sciences |
| GPA: |
3.90/4.00 |
| Expected
Graduation: |
June 2005 |
| Focus
of Research: |
Gene therapy provides a viable treatment alternative for an array
of diseases and disorders. Due to the well-known toxicity and immunogenicity
of viral vectors, the development of synthetics delivery systems is
gaining attention. Unfortunately, very little attention has been paid
to the pharmacokinetics and development of predictive models. The
overall goal of this proposal is to develop an understanding of the
pharmacokinetics (PK) and pharmacodynamics (PD) of liposome mediated
delivery of plasmid DNA and to utilize this information to develop
physiologically-based pharmacokinetic (PBPK) models. The incorporation
of ligand to the liposome: DNA complex should increase transfection
of the gene and minimize delivery and expression in untargeted cells/tissues.
This will be tested both in vitro and in vivo. Since synthetic DNA
has shown to target expression in endothelial cells, we extend to
incorporate a VEGF receptor ligand in hopes to further enhance delivery
to vascular endothelial cells, and later incorporate a gene to prohibit
angiogensis. Tumor zenograft models will be used to investigate the
PK and PD of vascular endothelium targeted gene therapeutics, and
validated PBPK models will be developed. |
| Title
of Dissertation: |
“Pharmacokinetic Optimization of Cancer Gene Therapy.” |
| Degrees
Received: |
B.S., Chemical Engineering, University of Minnesota, June 1999 |
| Honors
Received: |
1999-1996, Student of Color Tuition Waiver |
| AFPE
Award: |
USP-AFPE Association Fellowship in the Pharmaceutical Sciences |
|
JARED M. BROWN
University of Montana School of Pharmacy and Allied Health Sciences
|
| Major: |
Pharmacology/Toxicology |
| GPA: |
3.86/4.00 |
| Expected
Graduation: |
May 2004 |
| Focus
of Research: |
Utilizing a mouse model which develops autoimmune disease similar
to systemic lupus erythematosus following crystalline silica exposure,
I am working on the role of apoptosis and molecular mechanisms involved
in this disease process. |
| Title
of Dissertation: |
“Mechanisms of Silica and Induced Autoimmune Disease
in New Zealand Mixed Mice” |
| Degrees
Received: |
B.S., Microbiology, Colorado State University, May 1997 |
| Honors
Received: |
2003, AFPE Pre-Doctoral Fellowship; 2002, Best Student Presentation
2nd place, SOT Annual Meeting; 2002, UM Graduate Student Travel Award;
2002, Montana BRIN Travel Award |
| AFPE
Award: |
AAPS-AFPE Association Fellowship in the Pharmaceutical Sciences |
|
ANNA M. CALCAGNO
University of Kansas School of Pharmacy
|
| Major: |
Medicinal/Pharmaceutical Chemistry |
| GPA: |
3.83/4.00 |
| Expected
Graduation: |
May 2004 |
| Focus
of Research: |
The specific aim of my project is to determine the size and mechanism
of opening of the intercellular junctions created by E-Cadherin Derived
peptides. MDCK and Cac-2 cells will be studied. Understanding the
modulation of the intercellular junction will improve Paracellular
drug delivery. |
| Title
of Dissertation: |
“Modulation of Paracellular Permeability by E-Cadherin
Derived Decapeptides.” |
| Degrees
Received: |
M.S., Pharmaceutical Chemistry, University of Kansas, January 2002
M.S., Pharmaceutics, University of Michigan, May 1996
B.S., Pharmacy, West Virginia University, December 1993 |
| Honors
Received: |
2003-2002, AFPE Fellowship; 2002-2001 Iota Sigma Pi Honor Society;
2003-2000, NIH Biotech Training Grant; 2002-1999, Merck-Pharm. Chemistry
Tuition Fellowship; 1996-1995, AFPE Pre-doctoral Fellowship; 1996-1995,
NIH Pharmacological Sciences & Biorelated Chemistry Training Grant;
1994, Merck Fellowship; 1994 Phi Lambda Sigma-Glaxo-AFPE First Year
Graduate Fellowship; 1994, Lilly Achievement Award; 1994, Merck Award;
1993-1992, Rho Chi Pharmacy Honor Society |
| AFPE
Award: |
ABBOTT LABORATORIES-AFPE Fellowship in the Pharmaceutical Sciences |
|
RYAN CASE
University of Illinois at Chicago College of Pharmacy
|
| Major: |
Pharmacognosy |
| GPA: |
4.75/5.00 |
| Expected
Graduation: |
June 2006 |
| Focus
of Research: |
This research will focus on the documentation of plants used within
Manus Province, Papua New Guinea to treat malaria and tuberculosis,
and assessment of their potential to supplement treatment of malaria
and tuberculosis through chemical and biological analysis, and finally
to improve community awareness of herbal treatments for malaria and
tuberculosis. |
| Title
of Dissertation: |
“Scientific Validation of Plants Used by the People
of Manus Province, Papua New Guinea, to Treat Malaria and Tuberculosis” |
| Degrees
Received: |
B.S., Plant Biology, University of Delaware, January 2001 |
| Honors
Received: |
2003, Lloyd Yale Memorial Scholarship; 2003, Anne Chatham Award;
2001-1997, Carvel State Scholar; 2001-1997, Delaware Governor’s
Scholarship; 2000, Undergraduate Research Grant; 1999, Outstanding
Freshman Academics; 1999, Science And Engineering Scholar; 1998, First
Year Honors Certificate |
| AFPE
Award: |
AFPE Fellowship in the Pharmaceutical Sciences |
|
JAE H. CHANG
University of California at San Francisco School of Pharmacy
|
| Major: |
Medicinal/Pharmaceutical Chemistry |
| GPA: |
3.96/4.00 |
| Expected
Graduation: |
September 2004 |
| Focus
of Research: |
The focus of my research are transporters and metabolism. More specifically,
we are looking at how drugs that are predominantly glucuronidated
are affected by various drug transporters in the human intestine.
We hope that my research will allow us to understand a little more
regarding absorption; specifically, the role of transporters and metabolism
in absorption. Eventually we hope that our research will allow us
to predict and to manipulate human drug absoption. |
| Title
of Dissertation: |
“Interplay of UDP-glucuronsyltransferases and
Various Transporters in Drug Absorption” |
| Degrees
Received: |
B.S., Chemistry, Duke University, May 1997
B.A., History, Duke University, May 1997 |
| Honors
Received: |
2003, KSEA Merit Scholarship; 2003, AFPE Fellowship; 2001, Travel
Award; 2000-2001, Korean-American Student Merit; 1997-1993, Dean’s
List; 1993, FOCUS at Duke University |
| AFPE
Award: |
JOSIAH KIRBY LILLY SR. Memorial Fellowship in the Pharmaceutical
Sciences |
|
CHRISTINA M. CHARRIEZ
University of Kentucky College of Pharmacy
|
| Major: |
Pharmaceutical Sciences |
| GPA: |
3.74/4.00 |
| Expected
Graduation: |
May 2004 |
| Focus
of Research: |
The research focuses on the integration of drug metabolism, pharmacokinetics,
and pharmacodynamics to better understand the neurosciences and diseases
of the aging. |
| Title
of Dissertation: |
“Effect of Alzheimer’s Disease on CNS Cholinergic
Receptor Expression.” |
| Degrees
Received: |
B.S., Pharmacy, University of Florida, May 1999 |
| Honors
Received: |
2002-2001, AFPE Pre-doctoral Fellowship; 1999, Phi Kappa Phi Honor
Society; 1999, Golden Key National Honor Society; 1999, Mylan Pharmaceuticals
Award; 1999-1997, Dean’s Honor Roll |
| AFPE
Award: |
SCHERING-PLOUGH-AFPE Fellowship in the Pharmaceutical Sciences |
|
JENNIE Y. CHOU
University of Texas at Austin College of Pharmacy
|
| Major: |
Social & Administrative Sciences |
| GPA: |
4.00/4.00 |
| Expected
Graduation: |
May 2004 |
| Focus
of Research: |
Focus of research is on geriatric pharmacy and health policies related
to caring for older people in the long-term care setting. More specifically,
I am interested in the development of evidence-based guidelines for
improving the quality of care for elderly nursing home residents. |
| Title
of Dissertation: |
“Physicians’ Practice Behaviors Related
to Prescribing Angiotensin-Converting Enzyme Inhibitors (ACEIs) for
the Management of Congestive Heart Failure in Elderly Nursing Home
Residents.” |
| Degrees
Received: |
Pharm.D., University of Texas-Austin, December 2000
B.S., Pharmacy, The University of Texas-Austin, May 1996 |
| Honors
Received: |
2003-2002, AFPE Pre-Doctoral Fellowship; 2002-2001, Johnson and
Johnson Endowed Graduate Fellowship in Pharmacy; 2000, Texas Excellence
in Teaching Award |
| AFPE
Award: |
ASHP FOUNDATION-AFPE Fellowship in Social & Administrative
Sciences (Drug Misadventures/Patient Compliance) |
|
LINDSAY COMSTOCK
University of Wisconsin-Madison School of Pharmacy
|
| Major: |
Pharmaceutical Sciences |
| GPA: |
3.69 |
| Expected
Graduation: |
August 2005 |
| Focus
of Research: |
The primary research focus is to explore DNA modifying agents that
derive sequence specificity from DNA methyltransferases. Specifically,
they will be utilized in combination with Aziridine-based co factor
mimics. The resulting lesions will undergo further conjugation with
a DNA reactive Pharmacophore, creating conjugates capable of DNA damage. |
| Title
of Dissertation: |
"Aziridine Base Cofactor Mimics: Synthesis and
Biological Evaluation of Methyltransferase Dependent DNA Alkylation” |
| Degrees
Received: |
B.S., Chemistry, Northern Arizona University, May 2000 |
| Honors
Received: |
2000 Outstanding Chemistry Senior, 1997 Outstanding General Chemistry
Award |
| AFPE
Award: |
|
|
SCOTT R. CROY
University of Wisconsin-Madison School of Pharmacy
|
| Major: |
Pharmaceutical Sciences |
| GPA: |
3.89/4.00 |
| Expected
Graduation: |
May 2004 |
| Focus
of Research: |
Our principle focus is to study the effects of amphiphilic block
copolymers on the aggregation state of the Antifungal drug Nystatin.
The aggregation state of Nystatin defines its membrane toxicity, as
aggregated Nystatin is toxic to mammalian cells, while Nystatin unimers
are not. Block copolymers may allow for safe systemic administration
of Nystatin by interfering with its self-aggregation. |
| Title
of Dissertation: |
“Effects of Amphiphiles on the Aggregation and
Toxicity of Nystatin.” |
| Degrees
Received: |
Pharm.D., Pharmacy, Drake University, May 1999 |
| Honors
Received: |
2002, AFPE Pre-Doctoral Fellowship; 2001, Rennebohm Teaching Assistant
Award; 1999, Pfizer Fellowship; 1998, NASA Fellowship; 1997, Kresge
Fellowship; 1997, Pfizer Industry Internship; 1998-1996, Drake University
President’s List; 1995, Alpha Lambda Delta Honor’s Society;
1999-1994, Drake University Trustee’s Scholarship; 1996-1994,
Drake University Dean’s List |
| AFPE
Award: |
APhA-AFPE Association Fellowship in the Pharmaceutical Sciences |
|
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