NIMA
AKHAVEIN |
Mercer
University Southern School of Pharmacy |
| Major
|
Pharmaceutics |
| GPA: |
3.88/4.00 |
| Graduation
Date: |
May 2007 |
| Focus
of Research: |
To use microspheres
made from biocompatible polymers to essentially encapsulate the
NF-kB antisense oligonucleotides (ASO). NF-kB is a transcription
factor, which is largely responsible for the production of various
pro-inflammatory cytokines, such as IL-1, IL-6, and TNF-alpha,
which are largely responsible for the chronic inflammation associated
with rheumatoid arthritis. It is, therefore, appropriate that
NF-kB can be a common target for the treatment of rheumatoid arthritis,
which affects 2.1 million Americans.. It is hypothesized this
strategy will increase the stability and biological half-life
of the ASO and also condense the ASO so that it can be more efficiently
phagocytosed by cells such as macrophages, which play a large
role in the production and release of pro-inflammatory cytokines.
|
| Title
of Dissertation: |
“Microsphere
Delivery of Antisense NF-kappa B Oligonucleotide.” |
| Degrees
Received: |
B.A., Psychology,
Mercer University, May 2003 |
| Honors
Received: |
2006-05,
AFPE Pre-Doctoral Fellowship; 2003, Richard Metzger Award for
Best Psychology Research, Dean’s List; 2003-00, Atlantic
Sun All Academic Conference; 2002, NCAA Foundation Leadership
Committee Nominee; 2000, Trans America Athletic All Academic Conference |
| AFPE
Award: |
Novartis-
AFPE Pre-Doctoral Fellowship in Pharmaceutical Science |
CHARLENE A. BAKSH |
University
of Maryland Baltimore School of Pharmacy |
| Major
|
Clinical
Pharmaceutical Sciences (pharmacokinetics) |
| GPA:
|
3.58/4.0 |
| Graduation
Date: |
December
2007 |
| Focus
of Research: |
To study
the clinical pharmacology and pharmacodynamics of UCN-01by implementing
a Phase I clinical investigation of UCN-01 in combination with
perifosine in patients with refractory acute leukemia. UCN-01
is a potent inhibitor of phosphotidylinositide dependent kinase-1(PDK-1),
which is responsible for acting on akt to phosphorylate Thr-308
after its recruitment to the plasma membrane by binding through
its prekstrin homology domain to phosphorylated phosphotidylinostides. |
| Title
of Dissertation: |
“Clinical
Pharmacology and Pharmacodynamics of Phosphotidylinositide Dependent
Kinase-1 Inhibitor 7-hydroxystaurosporine (UCN-01) in Refractory
Acute Leukemia.” |
| Degrees
Received: |
Pharm.D.,
University of Maryland Baltimore, May 2004 |
| Honors
Received: |
2006, AFPE
Pre-Doctoral Fellowship; 1999, Outstanding Academic Achievement
as a Sophomore |
| AFPE
Award: |
Cline, Davis
& Mann, Inc - AFPE Pre-Doctoral Fellowship in the Pharmaceutical
Sciences |
JOHN D. BAUER |
Mercer
University Southern School of Pharmacy |
| Major
|
Medicinal/Pharmaceutical
Chemistry |
| GPA:
|
3.59/4.0 |
| Graduation
Date: |
May 2007 |
| Focus
of Research: |
To modify
the aryl-acetic template of CDB, characteristic of nonselective
COX inhibitors, to one in which the carboxylic acid moiety is
modified into a nitric oxide donating moiety that will provide
an ulcerogenic sparing NSAID. |
| Title
of Dissertation: |
“The
Designs, Synthesis, and Evaluation of Novel m-Terphenyl Derivatives
as Non-steroidal Anti- Inflammatory Agents.” |
| Degrees
Received: |
B.S., Biochemistry,
State University of New York at Binghamton, May 2001 |
| Honors
Received: |
2006, AFPE
Pre-Doctoral Fellowship; 2005, Pharmor Scholarship, 2005, 1st
Place SEPS Platform Presentations; 2002, 2003 Patrick J D’Souza
Award; 2002,2003, Pharmacy Dean’s Award |
| AFPE
Award: |
Pfizer, Inc
- AFPE Pre-Doctoral Fellowship in Pharmaceutical Science |
KATHERINE M. BLOCK |
University
of Arizona College of Pharmacy |
| Major
|
Medicinal/Pharmaceutical
Chemistry |
| GPA:
|
4.0/4.0 |
| Graduation
Date: |
May 2009 |
| Focus
of Research: |
To design
highly specific chemotherapeutic agents that will reduce the deleterious
effects of radiation therapy by synthesizing avb3 - selective
peptidic and small molecule ligands linked to a polyester dendritic
scaffolding and couple them with carborane clusters to provide
a high load of radioactive boron to cancerous cells. In order
to block the angiogenic process that accompanies tumor growth
and metastasis, we are utilizing peptide ligands to selectively
deliver carborane clusters to the tumor site for use in Boron
Capture Neutron Therapy. |
| Title
of Dissertation: |
“Multivalent
Integrin Antagonists for Cancer Imaging and Therapy.” |
| Degrees
Received: |
B.S., Chemistry,
University of Missouri-St. Louis, May 2001 |
| Honors
Received: |
2006, AFPE
Pre-Doctoral Fellowship, Achievement Rewards for College Scientist
(ARCS); 2005, Ruth Kirschtein National Research Service Award;
2001, Alan F. Berndt Outstanding Senior Chemist Award, American
Chemical Society’s Award for Analytical Chemistry, Placed
1st in seminar competition at American Chemical Society’s
Undergraduate Research Symposium; 2000, William and Erma Cooke
Chemistry Fellowship, Monsanto Air to Education Scholarship in
Chemistry |
| AFPE
Award: |
Ernest Mario
Endowed AFPE Pre-Doctoral Fellowship in the Pharmaceutical Sciences |
CELESTE M. BOLIN |
University
of Montana Skaggs School of Pharmacy |
| Major
|
Pharmacology/Toxicology |
| GPA:
|
3.75/4.00 |
| Graduation
Date: |
May 2008 |
| Focus
of Research: |
To determine
the effect of oxidized guanosine triphosphate (GTP) on the activity
of the key enzyme soluble guanylyl cyclase (sGC) involved in learning
and memory. The goal is to elucidate mechanistic changes in neurons
that contribute to learning deficits during development such as
attention deficit disorder and to the early-stage Alzheimer’s
Disease (AD) memory loss in adults that precedes gross pathological
AD changes in the brain. Elucidating this damage pathway could
provide preventive and therapeutically-relevant advances toward
treatment of learning deficits seen in children who have been
exposed to toxins that promote oxidative stress as well adults
suffering from AD. |
| Title
of Dissertation: |
“Oxidized
GTP and the Brain: Effects on Learning and Memory with Implications
for Alzheimer’s Disease.” |
| Degrees
Received: |
B.A.,
Chemistry, Whitman College, May 2001 |
| Honors
Received: |
2006, AFPE
Pre-Doctoral Fellowship; 2004, NSF-EPSCoR Fellowship; 2000-98,
Honors for GPA Whitman |
| AFPE
Award: |
Accreditation
Council for Pharmacy Education - AFPE Pre-Doctoral Fellowship
in the Pharmaceutical Sciences |
JENNIFER J. BONNER |
University of Pittsburgh School of Pharmacy |
| Major
|
Pharmacokinetics/Metabolism |
| GPA:
|
4.0/4.0 |
| Graduation
Date: |
December
2008 |
| Focus
of Research: |
To conduct
pharmacokinetic studies in small bowl transplant recipients and
healthy control patients using orally-administered probe substrates
for CYP3A4/5 and p-glycoprotein to assess the effects of time
as well as CYP3A4/5 and MDRI (the gene that encodes p-glycoprotein)
genotype on oral bioavailability of drugs following small bowel
transplantation. The purpose is to understand pharmacokinetic
alterations after small bowel transplantation, especially changes
in intestinal first-pass metabolism and bioavailability. |
| Title
of Dissertation: |
“Short-term
and Long-term Effects of Small Bowel Transplantation on Drug Absorption
and First-pass Metabolism.” |
| Degrees
Received: |
Pharm.D.,
University of Maryland, Baltimore, May 2003
B.A., History, The College of Wooster, October 1990 |
| Honors
Received: |
2006, AFPE
Pre-Doctoral Fellowship; 2003, Perrigo Award for excellence in
nonprescription medication studies |
| AFPE
Award: |
Pfizer Inc.
- AFPE Pre-Doctoral Fellowship in the Pharmaceutical Sciences |
MARK P. BORGMAN |
University
of Maryland, Baltimore School of Pharmacy |
| Major
|
Pharmaceutical
Sciences |
| GPA:
|
3.73/4.00 |
| Graduation
Date: |
March 2009 |
| Focus
of Research: |
To research
the targeted delivery of bioactive and diagnostic agents to solid
tumors using polymeric biomaterials. The project is at the interface
of novel delivery system research and translation nuclear medicine.
Critical challenges in this area of drug delivery research are
mastering the synthesis and characterization of novel delivery
systems as well as achieving successful clinical translations
that selectively target the site of action while minimizing toxicity
to background organs. |
| Title
of Dissertation: |
“N-(2-hydroxypropyl)
Methacrylamide (HPMA) Copolymer-Peptide Conjugates for Angiogenesis
Targeted Delivery of Diagnostic and Therapeutic Radionuclides.” |
| Degrees
Received: |
B.S., Medical
Technology, Michigan State University, May 2004 |
| Honors
Received: |
2006, AFPE
Pre-Doctoral Fellowship; 2004, Academic Honors MSU Medical Technology;
2004-03, Dean’s Honor Roll |
| AFPE
Award: |
Wyeth - AFPE
Pre-Doctoral Fellowship in the Pharmaceutical Sciences |
EVE E. BRALLEY |
University
of Georgia College of Pharmacy |
| Major
|
Pharmacology/Toxicology |
| GPA:
|
3.9/4.0 |
| Graduation
Date: |
August 2007 |
| Focus
of Research: |
To study
the anti-inflammatory properties of the muscadine grape both in
in-vivo and in-vitro models as a model of nutraceutical research
and development. |
| Title
of Dissertation: |
“Effect
of Muscadine Grapes in Models of Inflammation.” |
| Degrees
Received: |
C.C.N., Certified
Clinical Nutritionist, Clinical Nutrition Certification Board,
August 2000
B.S., Nutrition Science, University of Georgia, December 1999 |
| Honors
Received: |
2006, AFPE
Pre-Doctoral Fellowship; 2005-04, AFPE Fellowship; 2004, Award
for Outstanding Teaching Assistant; 1996, Phi Upsilon Omicron
Honor’s Fraternity, National Golden Key Club Member |
| AFPE
Award: |
American
Pharmacists Association - AFPE Pre-Doctoral Fellowship in the
Pharmaceutical Sciences |
IRA S. BUCKNER |
University
of Iowa College of Pharmacy |
| Major
|
Pharmaceutics |
| GPA:
|
4.0/4.0 |
| Graduation
Date: |
May 2007 |
| Focus
of Research: |
To investigate
the magnitude, mechanism, and implications of compaction induced
changes in the thermodynamic properties of many pharmaceutical
materials using conventional thermodynamic, mechanical and structural
analyses in conjunction with data generated using a unique compression
calorimeter. Further understanding of the relationship between
material properties and their response to compacting will support
more efficient and successful development of pharmaceutical products. |
| Title
of Dissertation: |
“Investigations
into the Thermodynamic Changes Induced by Compaction of Pharmaceutical
Materials.” |
| Degrees
Received: |
B.S., Chemistry,
Illinois State University, May 1999 |
| Honors
Received: |
2006, AFPE
Pre-Doctoral Fellowship; 2006-02, UI Presidential Graduate Fellowship;
2005-04, AFPE Pre-Doctoral Fellowship; 2004-03, Keith Guillory
Fellowship; 2000, Abbott Laboratories Performance Excellence Award;
1998, ACS Analytical Undergraduate Award, Hypercube Physical Chemistry
Award |
| AFPE
Award: |
American
Association of Pharmaceutical Scientists - AFPE Pre-Doctoral Fellowship
in the Pharmaceutical Sciences |
AMY L. BURDETTE |
University
of Georgia College of Pharmacy |
| Major
|
Pharmacology/Toxicology |
| GPA:
|
3.86/4.0 |
| Graduation
Date: |
August 2007 |
| Focus
of Research: |
To examine
the anti-glycating and hypocholesterolemic actions or sorghum
and muscadines, and to develop animal models to demonstrate these
agent’s lipid altering and anti-glycating capabilities.
Dietary supplements and functional foods can prevent the glycation
of proteins and do possess cholesterol lowering capabilities without
harmful side effects. For these reasons, nutraceutical agent development
is a growing trend. |
| Title
of Dissertation: |
“The
Effects of Sorghum Bran and Muscadine Grapes on Glycation Product
Formation in the Fructose Fed Animal.” |
| Degrees
Received: |
B.S., Chemistry,
Georgia College and State University, May 2003 |
| Honors
Received: |
2006, AFPE
Pre-Doctoral Fellowship; 2005, AFPE Fellowship, Most Valuable
Teaching Assistant; 2003, Most Valuable Chemistry Major, Lucy
Blake Carson Chemistry Scholarship, Kappa Mu Epsilon Fraternity;
2003-99 Dean’s Honors List |
| AFPE
Award: |
Consumer
Healthcare Products Association - AFPE Pre-Doctoral Fellowship
in the Pharmaceutical Sciences |
AMY B. CADWALLADER |
University
of Utah College of Pharmacy |
| Major
|
Pharmacology/Toxicology |
| GPA:
|
3.88/4.00 |
| Graduation
Date: |
December
2007 |
| Focus
of Research: |
To test the
hypothesis that anabolic-androgenic steroids (AAS) have multiple
mechanisms of action including activation of the hAR, repression
of hGR activity via competitive antagonism, and repression of
hGR activity via co-activator squelching. The specific contribution
of direct ligand-mediated glucocorticoid antagonism and its relationship
to hAR and resulting activity have not been demonstrated and interactions
between hAR and hGR and co-activators have not been assessed.
AAS are known to have varying anabolic and androgenic properties.
However, the relationship between AAS and hAR activity, anti-glucocortoid
activity, and co-activator contributions has not been made. |
| Title
of Dissertation: |
“Mechanism
of Action of Anabolic-Androgenic Steroids.” |
| Degrees
Received: |
M.S., Biology,
Virginia Commonwealth University, May 2003
B.S., Chemistry/Biochemistry & Molecular Biology, Dickinson
College, May 2001 |
| Honors
Received: |
2006-05,
AFPE Pre-Doctoral Fellowship; 2004, Society of Toxicology Graduate
Student Travel Award, U of U Graduate Research Supplemental Travel
Award; 2003, Willard L. Eccles Merit Fellowship-University of
Utah; 2001, Alumni Council Leadership Award-Dickinson College;
2000, John E. Benson Handbook Award-Dickinson College |
| AFPE
AWARD: |
Josiah Kirby
Lilly Sr. Memorial AFPE Pre-Doctoral Fellowship in the Pharmaceutical
Sciences |
VIVIEN Y. CHEN |
University
of Michigan College of Pharmacy |
| Major
|
Pharmaceutics |
| GPA:
|
3.83/4.00 |
| Graduation
Date: |
December
2007 |
| Focus
of Research: |
To investigate
the sequestration of drug in the cytosol as a mechanism of drug
efflux that could potentially be contributing to the resistance
of cancer cells to chemotherapy. This research addresses the problem
of multi-drug resistance (MDR) in cancer chemotherapy and seeks
to reveal new class of targets for use in combating cancer. |
| Title
of Dissertation: |
“The
Impact of Vesicle Trafficking on Intracellular Pharmacokinetics
and Pharmacodynamics.” |
| Degrees
Received: |
M.S., Pharmaceutics,
University of Michigan, September 2004
B.S., Biology, Duke University, May 2001 |
| Honors
Received: |
2006, AFPE
Pre-Doctoral Fellowship; 2005, PhRMA Pre-Doctoral Fellowship;
2004-03, NIH PSTP Fellowship; 2002, Parke-Davis/Warner-Lambert
Fellowship; 1997, Robert E. Byrd Scholarship |
| AFPE
Award: |
Wyeth - AFPE
Pre-Doctoral Fellowship in the Pharmaceutical Sciences |
PADMANABH CHIVUKULA |
University
of Utah College of Pharmacy |
| Major
|
Pharmaceutics |
| GPA:
|
3.87/4.00 |
| Graduation
Date: |
May 2007 |
| Focus
of Research: |
To evaluate
the use of an oral colon specific hydrogel delivery system for
the delivery of bioactive molecules in the treatment of colorectal
cancer (CRC). The research encompasses the synthesis and evaluation
of IPN hydrogels composed from pH-sensitive aromatic azo group
containing hydrogel as the first component and a hydrolyzable
network as the second component to be used for diagnosis and treatment
of colorectal cancer. |
| Title
of Dissertation: |
“Interpreting
Hydrogel Networks and Their Application in Colon Cancer Imaging
and Treatment.” |
| Degrees
Received: |
B.S., Chemistry,
University of Utah, June 2001 |
| Honors
Received: |
2006, AFPE
Pre-Doctoral Fellowship; 2005-04, AFPE Pre-Doctoral Fellowship |
| AFPE
Award: |
Richard E.
Faust Citation AFPE Pre-Doctoral Fellowship in the Pharmaceutical
Sciences |
LISA D. COLES |
University
of Maryland School of Pharmacy |
| Major:
|
Pharmaceutical
Sciences |
| GPA:
|
3.89/4.00 |
| Graduation
Date: |
August 2008 |
| Focus
of Research: |
To define
how the gestational period affects the placental and blood-to-brain
transport and maternal pharmacokinetics of drugs and subsequent
fetal exposure. Specific drugs of interest include substrates
of P-glycoprotein such as HIV protease inhibitors. This project
is designed to increase our knowledge of how gestational age affects
the transfer of drugs to the mother’s brain and fetus and
to aid in the assessment of the clinical risk/benefit of drugs
in pregnant women. |
| Title
of Dissertation: |
“Changes
in Blood Brain Barrier and Placental Distribution of P-glycoprotein
Substrates During Pregnancy.” |
| Degrees
Received: |
M.S., Biomedical
Engineering, University of Minnesota, February 2000
B.S., Chemical Engineering, Iowa State University, December 1996 |
| Honors
Received: |
2006, AFPE
Pre-Doctoral Fellowship, Rho Chi Honor Society; 1996, Iowa State
Honors; 1994, Omega Chi Epsilon Honor Society (Chem. Eng.) |
| AFPE
Award: |
CVS Corporation
- AFPE Pre-Doctoral Fellowship in the Pharmaceutical Sciences |
KELLY L. DAMM |
University
of Michigan College of Pharmacy |
| Major
|
Medicinal/Pharmaceutical
Chemistry |
| GPA:
|
3.98/4.00 |
| Graduation
Date: |
September
2007 |
| Focus
of Research: |
To evaluate
experimental structures of HIV-1p, NMR ensembles and collection
of x-ray structures, as a source of multiple conformations to
generate receptor-based MPS pharmacophore models. The use of MPS
allows us to sample a range of conformational space and replicate
the inherent flexibility of a protein. The pharmacophore models
will be analyzed to determine features that differentiate susceptible
and resistant strains of HIV-1p. The resulting models will be
screened against large commercially available databases to predict
novel leads for the development of a broad spectrum HIV-1p inhibitor
that can overcome resistance liabilities of existing treatments.
|
| Title
of Dissertation: |
“Protein
Flexibility in Structure-based Drug Design.” |
| Degrees
Received: |
M.S.E., Biomedical
Engineering, University of Michigan, April 2002
B.S.E., Material Science Engineering, University of Michigan,
April 2002 |
| Honors
Received: |
2006, AFPE
Pre-Doctoral Fellowship; 2005-04, Harold and Vivian Shapiro Award,
Pharmaceutical Science Training Program; 2002-97, Adolf Wurst
Engineering Scholarship |
| AFPE
Award: |
Novartis
Pharmaceuticals - AFPE Pre-Doctoral Fellowship in the Pharmaceutical
Sciences |
GREGORY W. DANIEL |
University
of Arizona College of Pharmacy |
| Major
|
Social &
Administrative Sciences |
| GPA:
|
4.0/4.0 |
| Graduation
Date: |
May 2007 |
| Focus
of Research: |
To use administrative
claims data to study pharmacoepidemiology and health outcomes
within defined subsets of the population and to study the utilization
and expenditures associated with health services and prescription
drugs. |
| Title
of Dissertation: |
“Development
of Predictive Models Using Different Data Sources to Identify
Medicare Part Beneficiaries at Risk for High Prescription Drug
Expenditures" |
| Degrees
Received: |
M.P.H., Public
Health (Biostatistics), Ohio State University, August 2002
M.S., Pharmaceutical Administration, Ohio State University, December
2001
B.S., Pharmacy, Ohio State University, June 2000, Cum Laude with
Honors and Distinction |
| Honors
Received: |
2006, AFPE
Pre-Doctoral Fellowship |
| AFPE
Award: |
Robert Wood
Johnson Memorial AFPE Pre-Doctoral Fellowship in the Pharmaceutical
Sciences |
NATHANAEL DIRKS |
University
of Tennessee College of Pharmacy |
| Major
|
Pharmaceutical
Sciences |
| GPA: |
4.0/4.0 |
| Graduation
Date: |
May 2008 |
| Focus
of Research: |
To identify
exposure parameters (e.g. observed maximum concentration, area
under the curve, and duration of therapy), genetic factors, and
other demographic variables that may predispose a patient to HER1/EGFR
inhibitor-associated rash. The research incorporates pharmacometrics
and pharmacogenetics in the drug development process to optimize
drug efficacy and minimize drug toxicity. |
| Title
of Dissertation: |
“Identification
of Pharmacokinetic, Genetic, and Demographic Factors Predisposing
Patients to Rash Associated with Cetuximab, a HER1/EGFR Targeted
Monoclonal Antibody.” |
| Degrees
Received: |
Pharm.D.,
University of Tennessee, May 2005
B.A., Biology: Biomedical, University of Northern Iowa, May 2001 |
| Honors
Received: |
2006, AFPE
Pre-Doctoral Fellowship; 2005, Valedictorian, University of Tennessee
College of Pharmacy, Lilly Achievement Award, Medicinal Chemistry
Award; 2004-03, Seldon D. Feurt Memorial Scholarship; 2002, Plough
Scholarship, UNI Merchant Scholarship; 2001, Seldon D. Feurt Scholar
(Pharm.D./Ph.D. scholarship), University of Northern Iowa Purple
and Old Gold Award |
| AFPE
Award: |
GlaxoSmithKline
- AFPE Pre-Doctoral Fellowship in the Pharmaceutical Sciences |
JAMES A. DOWELL |
University
of Wisconsin-Madison School of Pharmacy |
| Major
|
Pharmaceutical
Sciences |
| GPA:
|
3.71/4.00 |
| Graduation
Date: |
August 2008 |
| Focus
of Research: |
To develop
improved mass spectrometry methods in the analysis of mammalian
neuropeptides in order to better understand the involvement of
neuropeptides in feeding and addiction. The discovery of novel
neuropeptides involved in feeding and addiction may enable the
development of new drug therapies to treat obesity. |
| Title
of Dissertation: |
“Mammalian
Neuropeptides Involved in Feeding and Addiction.” |
| Degrees
Received: |
B.A., Chemistry,
University of Kansas, December 1998 |
| Honors
Received: |
2006, AFPE
Pre-Doctoral Fellowship; 2003, Mern Kier Fellowship in Pharmacy
|
| AFPE
Award: |
GlaxoSmithKline
- AFPE Pre-Doctoral Fellowship in the Pharmaceutical Sciences |
DEREK A. DRECHSEL |
University
of Colorado at Denver and Health Sciences Center School of Pharmacy |
| Major: |
Pharmacology/Toxicology |
| GPA: |
3.88/4.00 |
| Graduation
Date: |
May 2009 |
| Focus
of Research: |
To elucidate
the mechanisms of oxidative damage and neuronal cell death in
Parkinson’s Disease (PD) by examining the neurotoxic consequences
of over-expression and under-expression of mitochondrial aconitase.
The modulation of aconitase levels can be expected to affect aspects
of PD pathogenesis such as TCA cycle function, iron accumulation,
and the resulting oxidative damage due to reactive oxygen species.
By examining events occurring during the cell death process of
Parkinson’s Disease, this research hopes to gain insight
into mechanisms that could be used to enhance cell survival. |
| Title
of Dissertation: |
“Changes
in Mitochondrial Aconitase Expression Modulate Neuotoxicity in
Models of Parkinson’s Disease.” |
| Degrees
Received: |
B.S., Biology,
Pennsylvania State University, December 2003 |
| Honors
Received: |
2006, AFPE
Pre-Doctoral Fellowship; 2003, Eberly College of Science Recognition
of Research; 2002, USCSA Academic All-American Award; 1999, Teamsters
Collegiate Scholarship Award |
| AFPE
Award: |
Healthcare
Distribution Management Association – AFPE Pre-Doctoral
Fellowship
in the Pharmaceutical Sciences |
JOHN S. DUNN |
University
of Colorado at Denver and Health Sciences Center School of Pharmacy |
| Major
|
Pharmaceutical
Sciences |
| GPA:
|
3.75/4.00 |
| Graduation
Date: |
May 2010 |
| Focus
of Research: |
To identify
a signaling pathway involved in the activity of the protein pharmaceutical,
phagocyte NADPH oxidase. Elucidation of this protein medication
would provide an important benefit in the further development
of a drug product based on tissue plasminogen activator (tPA)
which can more specifically target the anti-inflammatory activity
of the protein. This project will study the formulation of tPA
for pulmonary delivery but also explores the biological mechanism
of the anti-inflammatory activity of tPA protein. |
| Title
of Dissertation: |
“Cellular
Mechanism for the Modulation of the Phagocyte NADPH Oxidase by
Tissue Plasminogen Activator Formulated for Pulmonary Delivery.” |
| Degrees
Received: |
B.A., Biology,
University of Colorado at Colorado Springs, May 2002 |
| Honors
Received: |
2006 AFPE
Pre-Doctoral Fellowship; 2006-05, NIH Fellowship in Pharmaceutical
Biotechnology; 2005, Superior Spring Rotation Presentation Award;
2004, Colorado Graduate Education Fellowship Award; 2002, B.A.:
Graduated with Highest Distinction; 2001, Beta Beta Beta Biological
Honor Society |
| AFPE
Award: |
IMS Health
- AFPE Pre-Doctoral Fellowship in the Pharmaceutical Sciences |
KERRY M. EMPEY, Pharm.D. |
University
of Kentucky College of Pharmacy |
| Major
|
Pharmaceutical
Sciences |
| GPA:
|
3.91/4.00 |
| Graduation
Date: |
May 2007 |
| Focus
of Research: |
To ascertain
the role of clinically relevant, pharmacologically available cytokines,
such as GM-CSF, in expediting the clearance of neonatal pulmonary
infection. Neonatal mice treated with aerosolized heat-killed
Escherchia coli are able to clear Pneumocytis infection faster
than control neonatal mice, suggesting that it is possible to
stimulate the neonatal immune system exogenously. However, as
this is not a pharmacologically feasible option in the human population,
the research hypothesis is that neonatal mice treated with aerosolized
GM-CSF will be able to clear Pneumocytis infection faster secondary
to a stimulation in the number and function of alveolar macrophages
than their untreated controls. The research will also investigate
the potential benefit of combining GM-CSF with trimethoprim/sulfamethoxazole
to expedite clearance. |
| Title
of Dissertation: |
“Response
of Neonatal Alveolar Macrophages to Immunostimulation and Clearance
of Pneumocytis Infection.” |
| Degrees
Received: |
Pharm. D.,
University of Rhode Island, May 1999 |
| Honors
Received: |
2006, 2004,
AFPE Pre-Doctoral Fellowship; 2006-02, Dean’s List-University
of Kentucky; 1999, Merck Scholastic Achievement Award, Pharm.D.
with high distinction; 1999-94, Dean’s List-University of
Rhode Island, Golden Key National Honor Society; 1994-93, Dean’s
List-University of Maine |
| AFPE
Award: |
American
Association of Pharmaceutical Scientists - AFPE Pre-Doctoral Fellowship
in the Pharmaceutical Sciences |
PHILIP E. EMPEY |
University
of Kentucky College of Pharmacy |
| Major
|
Pharmaceutical
Sciences |
| GPA:
|
3.97/4.00 |
| Graduation
Date: |
March 2007 |
| Focus
of Research: |
To develop
a screening approach to identify xenobiotic/transporter interactions
that may be involved in drug accumulation in milk and to investigate
the molecular mechanisms of transporter gene regulation in mammary
epithelium. The goal is to identify xenobiotic transport proteins
in mammary epithelium with the goal of elucidating mechanisms
of drug accumulation in breast milk. Xenobiotic transport proteins
have been implicated in phenomena involving unexpected exposure
or response to medications. Models developed to predict neonatal
exposure do not explain the accumulation of many drugs in breast
milk. |
| Title
of Dissertation: |
“Xenobiotic
Transporter Gene Expression in Lactating Mammary Epithelium.” |
| Degrees
Received: |
Pharm.D.,
University of Rhode Island, May 1998 |
| Honors
Received: |
2006-2004,
AFPE Pre-Doctoral Fellowship; 2006, Certification of Completion,
K30 Clinical Research and Leadership Development Program; 2002,
Pre-Doctoral Fellow, NIH Reproductive Sciences Training Grant;
2001, BCPS Certification; 2001-00, Extra Mile Award, UK Pharmacy
Residency Programs; 1998, ACCP-Merck Undergraduate Research Scholar
Program Award; 1998-92, Dean’s List-University of Rhode
Island; 1993, Rho Chi High Scholastic Achievement Award |
| AFPE
Award: |
Merck Company
Foundation Endowed AFPE Pre-Doctoral Fellowship in the Pharmaceutical
Sciences |
RACHEL L. GRAVES |
University
of the Sciences-Philadelphia College of Pharmacy |
| Major:
|
Pharmaceutics |
| GPA:
|
4.0/4.0 |
| Focus
of Research: |
To use biodegradable
poly(lactide-co-glycolide) blended with polyethylene glycol as
scaffolds for bone regeneration applications. Different formulations
will be investigated to determine the effects of fabrication method
on thermal, mechanical, and degradation properties of scaffolds.
Scaffolds will also be investigated for immunogenicity, cell attachment,
and cell differentiation in-vitro and in-vivo. Biodegradable devices
containing growth factors are being investigated for the regeneration
of bone, cartilage, nerve, and skin. |
| Graduation
Date: |
May 2007 |
| Title
of Dissertation: |
“Biodegradable-PEG
Eluting Scaffolds for Bone Regeneration.” |
| Degrees
Received: |
B.S., Chemical
Engineering, Bucknell University, May 2002 |
| Honors
Received: |
2006, AFPE
Pre-Doctoral Fellowship, French-Gano-Kilmer-Pollard Fellowship;
2004, Rho Chi; 2002-98, Dean’s List-Bucknell University;
1998, Alpha Lambda Delta Honors Society |
| AFPE
AWARD: |
Merck Company
Foundation Endowed AFPE Pre-Doctoral Fellowship in the Pharmaceutical
Sciences |
XINYI D. GU |
University
of Michigan College of Pharmacy |
| Major
|
Pharmaceutics |
| GPA:
|
8.05/8.00 |
| Graduation
Date: |
December
2007 |
| Focus
of Research: |
To use different
complexation strategies to change the physical characteristics
of drugs such as nanoparticles and microspheres and different
delivery formulations to achieve extended release and targeting
specificity for existing and newly synthesized chemotherapeutic
agents. |
| Title
of Dissertation: |
“Nanoparticulate
Systems for Active Targeting of Chemotherapeutic Agents.” |
| Degrees
Received: |
B.S., Biochemistry,
University of Illinois-Urbana Champaign, May 2002 |
| Honors
Received: |
2006 AFPE
Pre-Doctoral Fellowship; 2003-02, Fred-Lyons Fellowship; 2002,
UIUC Bronze Tablet recipient; 2002-98, UIUC James Scholar |
| AFPE
Award: |
Pfizer Inc.
Endowed AFPE Pre-Doctoral Fellowship in the Pharmaceutical Sciences |
IGOR GUREVICH |
University
of Connecticut Storrs School of Pharmacy |
| Major: |
Pharmacology/Toxicology |
| GPA:
|
3.69/4.00 |
| Graduation
Date: |
May 2009 |
| Focus
of Research: |
To study
the mechanisms of interaction between retinoid receptors and a
novel coregulator recently isolated by our laboratory, and to
study the mechanisms by which this coregulator mediates transcriptional
repression. The novelty of this coregulator stems from its actions
as a corepressor of retinoic acid receptors (RAR) and Peroxisome
Proliferator Activated Receptors (PPAR) in the presence of ligands.
Retinoids are important in the several physiologic processes such
as vision and maintenance of epithelial tissues. |
| Title
of Dissertation: |
“Mechanisms
of Corepressor Recruitment by Nuclear Retinoid Receptors.” |
| Degrees
Received: |
B.S., Food
Sciences, University of Massachusetts, Amherst, May 2000 |
| Honors
Received: |
2006 AFPE
Pre-Doctoral Fellowship |
| AFPE
Award: |
Johnson &
Johnson Pharmaceutical R&D - AFPE Pre-Doctoral Fellowship
in the Pharmaceutical Sciences |
KIRK E. HEVENER |
University
of Tennessee College of Pharmacy |
| Major:
|
Medicinal/Pharmaceutical
Chemistry |
| GPA:
|
3.83/4.00 |
| Graduation
Date: |
Dec 2007 |
| Focus
of Research: |
To study
the structure-based design of novel antimicrobial agents, specifically
inhibitors of the bacterial enzyme dihydropteroate synthase, DHPS,
which is a key target in the bacterial folate biosynthesis pathway
and is not found in higher mammals. The research will use enzyme
crystal structures generated by our collaborators in a series
of computer-aided drug design techniques, including molecular
simulations, virtual screening, docking and scoring in order to
identify novel lead compounds which will then be synthesized and
tested for activity. |
| Title
of Dissertation: |
“The
Structure-Based Design of Novel Antibacterial Agents.” |
| Degrees
Received: |
B.S., Chemistry,
Tennessee State University, December 2005
Pharm.D., University of Tennessee, May 2005 |
| Honors
Received: |
2006, AFPE
Pre-Doctoral Fellowship, UT HSC Student Service Award; 2005, UT
ASP Outstanding Community Service Award, Who’s Who Among
Students in American Colleges and Universities; 2004, Imhotep
Leadership Society Inductee, Phi Delta Chi Whigham Award (Best
Brother); 2003, Phi Delta Chi Emerging Leader Award, UT ASP Top
10 ASP Member Award; 2001, Andrew D. Holt Alumni Scholarship Recipient |
| AFPE
Award: |
Pfizer Inc.
Endowed AFPE Pre-Doctoral Fellowship in the Pharmaceutical Sciences |
ELIZABETH J. HOHNADEL |
University
of Georgia College of Pharmacy |
| Major
|
Pharmacology/Toxicology |
| GPA:
|
3.7/4.0 |
| Graduation
Date: |
June 2007 |
| Focus
of Research: |
To investigate
the effects of chronic typical (haloperidal 1.0 mg/kg and 2.0
mg/kg) or atypical (risperidone 1.25 mg/kg and 2.5 mg/kg) neuroleptics
on working memory and sustained attention, and to determine biochemical
cholinergic correlates to the behavioral findings. 60 animals
will be divided into three cohorts of 20 to stagger the behavioral
testing. Identifying methods to optimize cholinergic activity
in the brain and performance of memory-related tasks in animal
models will facilitate future (clinical) efforts to identify optimal
therapies for cognitively impaired psychiatric patients. Chronic
treatment with typical neuroleptics may damage working memory
and executive function by disrupting the cholinergic system. Memory
function is the best predictor for long-term functional outcome
in schizophrenic patients. |
| Title
of Dissertation: |
“The
Central Cholinergic System as a Therapeutic Target for the Cognitive
Dysfunction of Schizophrenia.” |
| Degrees
Received: |
M.S., Biology,
Georgia College and State University, August 2001
M.Ed., Outdoor Education, Georgia College and State University,
December 1997
B.S., Biology, Presbyterian College, May 1992 |
| Honors
Received: |
2006, AFPE
Pre-Doctoral Fellowship, MCG Excellence in Research; 2006-04,
AFPE Pre-Doctoral Fellowship |
| AFPE
Award: |
Pfizer Inc.
– AFPE Pre-Doctoral Fellowship in the Pharmaceutical Sciences |
ERIN R. HOLMES |
University
of Mississippi School of Pharmacy |
| Major
|
Social &
Administrative Sciences |
| GPA:
|
3.86/4.0 |
| Graduation
Date: |
August 2007 |
| Focus
of Research: |
To understand
the role of emotions and emotional labor in work life outcomes
and the use of social effectiveness by pharmacists. Pharmacy management
issues in organizational behavior and human resource management. |
| Title
of Dissertation: |
“Dealing
with the Outcomes of Emotional Labor: What is the Role of Social
Effectiveness?” |
| Degrees
Received: |
M.S., Pharmacy
Administration, Duquesne University, July 2003
Pharm.D., Duquesne University, May 2001 |
| Honors
Received: |
2006, AFPE
Pre-Doctoral Fellowship, 2006, Graduate Achievement Award in Pharmacy
Administration-UM; 2006-03, Honors Fellow-UM Graduate School;
2005, Top Quality Peer Reviewer - Research in Social and Administrative
Pharmacy, AACP/Wal-Mart Annual Conference Scholarship Recipient;
2005-04, Teaching Assistant of the Year-UM School of Pharmacy;
2004, Student Research Paper of the Year-Department of Pharmacy
Administration; 2002, Coro (Pittsburgh) Health Science Fellow,
APhA-ASP McNeil Mortar & Pestle Professionalism Award National
Essay Contest Winner; 2001, APhA-ASP McNeil Mortar & Pestle
Professionalism Award-Duquesne University, Hugh C. Muldoon Academic
Pharmacy Award-Duquesne University; 2001-96, Dean’s List
(Duquesne University); 2000, Luis C. DiPaolo Academic Pharmacy
Award-Duquesne University; 2000-95, Chancellor’s Merit Award-Duquesne
University Full Academic Scholarship; 1999-97, Mylan School of
Pharmacy Academic Scholarships-DU; 1999-96, Strubb Merit Award-Duquesne
University Partial Academic Scholarship |
| AFPE
Award: |
Fred Eschelman
Endowed AFPE Pre-Doctoral Fellowship in the Pharmaceutical Sciences |
JOHN D. HULLEMAN |
Purdue
University School of Pharmacy and Pharmaceutical Sciences |
| Major
|
Medicinal/Pharmaceutical
Chemistry |
| GPA:
|
3.64/4.0 |
| Graduation
Date: |
May 2007 |
| Focus
of Research: |
To analyze
the protein DJ-1 that is associated with early-onset Parkinson’s
Disease and how oxidation of wild-type and mutant forms of DJ-1
changes their structural and functional characteristics. In addition,
the research will seek to identify ways of rescuing the activity
of mutant DJ-1 by promoting its dimerization. The research will
use structure-based drug screening to rationally select a small
set of pharmacologically-active molecules with potential to be
a lead compound in stabilizing active, mutant DJ-1 dimer. |
| Title
of Dissertation: |
"Characterizing
the Structural and Functional Differences Between Wild-type and
Mutant DJ-1.” |
| Degrees
Received: |
B.A., Biology,
University of Saint Thomas, May 2002, Cum Laude
B.A., Chemistry, University of Saint Thomas, May 2002, Cum Laude |
| Honors
Received: |
2006, AFPE
Pre-Doctoral Fellowship; 2006-05, Purdue University Incentive
Grant; 2005, Purdue Research Foundation Grant Award, Charles J.
Paget Travel Award; 2002-98, Saint Thomas Grant, Dean’s
Scholarship; 2001, John R. McQuillan Scholarship, Hillblom Foundation
Scholarship; 1999, Alliss Scholarship |
| AFPE
Award: |
Josiah Kirby
Lilly, Sr. Memorial AFPE Pre-Doctoral Fellowship in the Pharmaceutical
Sciences |
JILLIAN H. HURST |
University
of Georgia College of Pharmacy |
| Major
|
Pharmacology/Toxicology |
| GPA:
|
3.87/4.00 |
| Graduation
Date: |
May 2009 |
| Focus
of Research: |
To elucidate
the mechanism by which RGS 9-2 mediates signaling from drug targeted
G protein-coupled receptors (GPCRs) in the striatum. The Regulator
of G protein Signaling 9-2 (RGS 9-2) has been implicated in the
development of addiction and tolerance to cocaine and amphetamines.
Delineating the mechanism and specificity of RGS 9-2 interactions
with components of the GPCR signaling cascade may allow for the
rational design of agents to target pathways with greater specificity
than targeting the receptor itself. |
| Title
of Dissertation: |
“The
Role of Regulator of G protein Signaling 9-2 (RGS 9-2) in Gi-coupled
Striatal Signaling Pathways.” |
| Degrees
Received: |
B.S., Chemistry,
Mary Washington College, May 2004 |
| Honors
Received: |
2006 AFPE
Pre-Doctoral Fellowship; 2005, Outstanding Teaching Assistant-UGA;
2000, Mary Washington College Alumni Scholarship, Valedictorian-West
Springfield High School |
| AFPE
Award: |
GlaxoSmithKline
- AFPE Pre-Doctoral Fellowship in the Pharmaceutical |
PATRICE L. JACKSON |
Howard
University School of Pharmacy |
| Major
|
Medicinal/Pharmaceutical
Chemistry |
| GPA:
|
3.95/4.0 |
| Graduation
Date: |
August 2007 |
| Focus
of Research: |
To design,
synthesize and study biologically a novel series of methylated
and fluorinated enaminone thiazole derivatives as potential anticonvulsant
agents for the treatment of epilepsy. |
| Title
of Dissertation: |
“The
Synthesis of A Novel Series of Heterocyclic Thiazole Enaminone
Derivatives As Potential Anticonvulsants Agents.” |
| Degrees
Received: |
M.Sc., Chemistry,
Tennessee State University, May 2003, BS, Chemistry, LeMoyne-Owen
College, May 2000 |
| Honors
Received: |
2006, AFPE
Pre-Doctoral Fellowship; 2006-03, Chauncey Copper Scholarship;
2000, Memphis Chemical Association Scholar; 1999, National Dean’s
List, US Achievement Academy Scholar; 1999-98, Dean’s List,
LeMoyne-Owen College |
| AFPE
Award: |
Johnson &
Johnson Pharmaceutical R&D - AFPE Pre-Doctoral Fellowship
in the Pharmaceutical Sciences |
TARA L. JOHNSON |
Idaho
State University College of Pharmacy |
| Major: |
Pharmaceutical
Sciences |
| GPA: |
3.94/4.00 |
| Graduation
Date: |
August 2007 |
| Focus
of Research: |
To examine
signaling mechanisms and molecular markers of oral carcinogenesis
and to establish anticancer activity of isoflavones on dysplastic
and oral cancer cell lines. Preventive and therapeutic roles of
isoflavones in OSCC may be elucidated through the use of tumor
progression models. |
| Title
of Dissertation: |
“Effect
of Isoflavones on Oral Cancer Cell Lines, Premalignant Lesions,
and Adjacent Normal Oral Mucosa: A Mechanistic Study.” |
| Degrees
Received: |
M.Ed., Curriculum
and Instruction, Idaho State University, May 1992
B.S., Dental Hygiene, Idaho State University, May 1981 |
| Honors
Received: |
2006 AFPE
Pre-Doctoral Fellowship; 2004, Claudia Senekowitczh Summer Fellowship;
1999, Idaho State Board of Dentistry Appt. |
| AFPE
Award: |
Ortho-McNeil
Janssen Scientific Affairs - AFPE Pre-Doctoral Fellowship
in the Pharmaceutical Sciences |
JUHIENAH K. KHALAF |
University
of Kansas School of Pharmacy |
| Major: |
Medicinal/Pharmaceutical
Chemistry |
| GPA: |
3.83/4.00 |
| Graduation
Date: |
Summer 2007 |
| Focus
of Research: |
To understand
the synthesis and structure-activity relationship studies of complex
peptidyl nucleosides as antifungal agents by developing efficient
and flexible routes towards the synthesis of the ezomycin family
of compounds. Complex peptidyl nucleosides inhibiting a fungal
specific enzyme are currently being investigated as a new class
of antifungal agents. |
| Title
of Dissertation: |
“Studies
Towards the Total Synthesis of the Ezomycin Family of Antifungal
Antibiotics.” |
| Degrees
Received: |
M.S., Medicinal
Chemistry, University of Kansas, July 2004
B.S., Chemistry, Birzeit University (Palestine), May 2000 |
| Honors
Received: |
2006 AFPE
Pre-Doctoral Fellowship |
| AFPE
Award: |
National
Association of Boards of Pharmacy - AFPE Pre-Doctoral Fellowship
in the Pharmaceutical Sciences |
PHILLIP G. KOPF |
University
of New Mexico College of Pharmacy |
| Major
|
Pharmacology/Toxicology |
| GPA:
|
3.99/4.0 |
| Graduation
Date: |
May 2007 |
| Focus
of Research: |
To examine
the underlying mechanisms of the correlation of TCDD exposure
with cardiovascular disease that has been identified in human
epidemiology studies using a “state of the art” radiotelemetry
system to monitor blood pressure and heart rate. This toxicology
study is unique in that the exposure regimen is chronic exposure
to a lower dose of TCDD and thus more closely represents the pattern
of human patient exposure to TCDD. |
| Title
of Dissertation: |
“The
Effect of Sub-chronic, Low Level 2,3,7,8-tetrachlorodibenzo-p-dioxin
(TCDD) on the Development of Cardiovascular Disease.” |
| Degrees
Received: |
B.S., Biology,
Truman State University, May 2001 |
| Honors
Received: |
2006, AFPE
Pre-Doctoral Fellowship; 2006, WERC Fellowship; 2005, WERC Fellowship;
2004, Evans Charitable Trust Scholarship; 2003, BSGP Pathology
Scholar; 1997, National Russian Essay Contest-Gold Metal; 1996,
National Russian Essay Contest-Silver Metal |
| AFPE
Award: |
Josiah Kirby
Lilly, Sr. Memorial AFPE Pre-Doctoral Fellowship in the Pharmaceutical
Sciences |
HILLIARD KUTSCHER |
Rutgers
University Ernest Mario School of Pharmacy |
| Major
|
Pharmaceutical
Sciences |
| GPA:
|
3.89/4.00 |
| Graduation
Date: |
December
2007 |
| Focus
of Research: |
To develop
a biodegradable nanoparticle aggregate drug delivery system for
intravenous injection which passively targets the lung and actively
targets tumors. This project focuses on creating a nanoparticle
of a biodegradable material as well as a method for aggregating
of these particles in order to make a particle that targets the
lungs. Particle biodistribution will be studied using in-vivo
imaging. Plasma concentrations of an anticancer agent will be
determined by LC/ MS. Tumor reduction markers will be assessed
as the primary output parameter and histology samples will be
used to evaluate any adverse tissue inflammation due to the particles.
The structure of the drug delivery system will be engineered to
provide optimized drug release and elimination rates from the
body. |
| Title
of Dissertation: |
“Novel
Tumor-Targeted Nanoparticle Aggregates for the Treatment of Lung
Cancer.” |
| Degrees
Received: |
B.S., Chemical
Engineering, Clarkson University, May 2001 |
| Honors
Received: |
2006-05,
AFPE Pre-Doctoral Fellowship; 2001-97, Presidential Scholarship-Clarkson
University, Dean’s List-Clarkson University; 1999-97, Presidential
Scholar-Clarkson University; 1997, Eagle Scout |
| AFPE
Award: |
Ernest Mario
Endowed AFPE Pre-Doctoral Fellowship in the Pharmaceutical Sciences
|
HEATHER M. LEITNER |
University
of Colorado at Denver Health Sciences Center School of Pharmacy |
| Major
|
Pharmacology/Toxicology
|
| GPA:
|
3.82/4.00 |
| Graduation
Date: |
December
2007 |
| Focus
of Research: |
To develop
novel pharmacophores that overcome the selectivity barrier that
traditionally limits the potential clinical success of compounds
such as buthionine sulfoximine (BSO) as cancer therapy adjuncts.
The research focuses on targeting the ATP-dependent binding cassette
(ABC) transport genes that use glutathione (GSA) as a substrate
when expelling compounds from the cell. The goal is to utilize
this knowledge to develop compounds that selectively deplete cancer
cells of GSA. |
| Title
of Dissertation: |
“Selective
Modulation of Thiol Efflux in Cancer Therapy.” |
| Degrees
Received: |
M.S., Environmental
Science and Engineering, Colorado School of Mines, August 2002
B.S., EMS and Biology, Creighton University, August 2000 |
| Honors
Received: |
2006-05 AFPE
Fellowship; 1999-95 Reinert Scholarship; 1995, ASA Education Scholarship,
Westminster Elks Outstanding Student Award |
| AFPE
Award: |
Ortho-McNeil
Janssen Scientific Affairs - AFPE Pre-Doctoral Fellowship in the
Pharmaceutical Sciences |
THONG C. MA |
Ohio
State University College of Pharmacy |
| Major: |
Pharmaceutics |
| GPA: |
3.85/4.0 |
| Graduation
Date: |
June 2007 |
| Focus
of Research: |
To study
the mechanisms free 3-nitrotyrosine (3NT) neurotoxicity and its
role in Parkinson’s disease (PD) pathogenesis. Free-3NT
is an endogenous compound formed in oxidative environments and
is elevated in PD and in other neurodegenerative disorders. Its
injection into mouse brain causes PD-like neuron loss and is co-toxic
to neurons in cell culture. The generation and accumulation of
free-3NT may render neurons more susceptible to death and contribute
to neuronal loss in PD and other neurodegenerative disease. This
research characterizes the neurotonic effects of an endogenous
molecule that may contribute to neuron loss in Parkinson’s
Disease and other neurogenerative disorders. |
| Title
of Dissertation: |
“The
Molecular Mechanisms of Free-3-nitrotyrosine Neurotoxicity.” |
| Degrees
Received: |
B.S., Pharmacy,
Ohio State University, December 2001 |
| Honors
Received: |
2006-05 AFPE
Pre-Doctoral Fellowship; 2005, Ray Graduate Travel Award; 2002,
Marvin and Geraldine Faegles Memorial Award; 2001, Graduation
Summa Cum Laude with Honors |
| AFPE
Award: |
Sankyo Pharma
- AFPE Pre-Doctoral Fellowship in the Pharmaceutical Sciences
|
MOLLY E. MARTIN |
University
of Iowa College of Pharmacy |
| Major
|
Medicinal/Pharmaceutical
Chemistry |
| GPA:
|
3.97/4.0 |
| Graduation
Date: |
May 2007 |
| Focus
of Research: |
To develop
a short cationic peptide with a C-terminal inhibitory sequence
that can function to condense DNA, mediate cellular uptake, and
inhibit the proteasome. Once a potent inhibitor is designed, it
will be incorporated into a gene delivery system to determine
its effects on transfection and expression of gene therapy agents.
The proteasome is a multisubunit complex that is responsible for
the degradation of many cytosolic proteins. The use of a protease
inhibitor in this research could prevent premature metabolism
of a peptide-DNA condensate and possibly increase the gene transfer
efficiency of a non-viral gene delivery system. |
| Title
of Dissertation: |
“Design
of Novel Peptide Inhibitors of the Proteasome to Increase Gene
Transfer Efficiency.” |
| Degrees
Received: |
B.A., Chemistry,
Augustana College, May 2002 |
| Honors
Received: |
2006, ASGT
Meeting Travel Grant; 2006-04, AFPE Pre-Doctoral Fellowship; 2005-04,
Pharmacy Graduate Program Excellence Award; 2003, Center for Biocat.
& Bioproc. Pre-Doctoral Fellowship; 2002, University of Iowa
MNPC Fellowship; 1999, Dow Chemistry Scholarship |
| AFPE
Award: |
American
Association of Colleges of Pharmacy - AFPE Pre-Doctoral Fellowship
in the Pharmaceutical Sciences |
DAVE A. MILLER |
University
of Texas at Austin College of Pharmacy |
| Major
|
Pharmaceutics |
| GPA:
|
4.0/4.0 |
| Graduation
Date: |
May 2007 |
| Focus
of Research: |
To improve
the dissolution rate and bioavailability of Biopharmaceutical
Classification System (BSC) Class II drugs using a novel delivery
system produced via fine particle engineering technologies and
hot-melt extrusion. The goal of my research is to combine these
two technologies to produce compositions that improve the dissolution
rate of poorly water-soluble drugs and exhibit excellent storage
stability. |
| Title
of Dissertation: |
“Investigation
of the Physicochemical Properties of Solid Dispersions of Fine
Drug Particles in a Stabilizing Polymeric Carrier for Use in Drug
Delivery Applications.” |
| Degrees
Received: |
B.S., Chemical
Engineering, University of Texas at Austin, December 2002 |
| Honors
Received: |
2006-05,
AFPE Pre-Doctoral Fellowship; 2004, Rho Chi Pharmacy Honor Society;
2006, Who’s Who Among American Universities; 2002-01, Chemical
Engineering Departmental Scholarship, Honors Day Collegiate Scholar
Award; 2000, National Society of Collegiate Scholars; 1999, Alpha
Lambda Delta and Phi Eta Sigma Honor Societies |
| AFPE
Award: |
AstraZeneca
- AFPE Pre-Doctoral Fellowship in the Pharmaceutical Sciences |
BETH E. MISKIMINS |
University
of Iowa College of Pharmacy |
| Major
|
Medicinal/Pharmaceutical
Chemistry |
| GPA: |
3.81/4.00 |
| Graduation
Date: |
December
2008 |
| Focus
of Research: |
To study
interactions between cationic antimicrobial peptides, which have
been found to be instrumental in the clearance of infections,
and polyanion-based therapeutics and glycosaminoglycans in order
to test the hypothesis that specific endogenous glycosaminoglycans
and exogenous sulfated polysaccharide therapeutics are direct
and indirect effectors of specific cationic antimicrobial peptides.
Evaluating glycosaminoglycans and polyanion-based therapeutics
for the inhibition of antimicrobial activity and for binding affinity
for cationic antimicrobial peptides will help elucidate the role
glycosaminoglycans and polyanionic therapy play in modulating
the activity of these important immune system components. |
| Title
of Dissertation: |
“Modulation
of Human Antimicrobial Peptides by Endogenous Glycosaminoglycans
and Polyanionic Saccharide-based Therapeutics.” |
| Degrees
Received: |
B.S., Microbiology
and Biochemistry, Iowa State University, May 2004 |
| Honors
Received: |
2006, AFPE
Pre-Doctoral Fellowship; 2004, MNPC Fellowship, BBMB Department
Senior Award, Phi Beta Kappa Honor Society Membership; 2002, Shillinglaw
Memorial Scholarship; 2001, Golden Key National Honors Society
Membership, Phi Kappa Phi Honor Society Membership; 1999, State
of Iowa Scholar |
| AFPE
Award: |
Novo Nordisk
- AFPE Pre-Doctoral Fellowship in the Pharmaceutical Sciences |
SARAH J. NEHM |
University
of Michigan College of Pharmacy |
| Major
|
Pharmaceutics |
| GPA:
|
3.73/4.00 |
| Graduation
Date: |
May 2008 |
| Focus
of Research: |
To develop
a more rational screening method for cocrystals as well as to
study the pharmaceutical properties of these cocrystals. Current
methods to design cocrystals are empirically based and suffer
the risk of crystallizing the single component phases. The cocrystals
for which pharmaceutical properties have been studied are few,
and thus more research in this area is needed. Pharmaceutical
cocrystals are being studied for their ability top control the
pharmaceutical properties of the drug, such as dissolution, solubility,
and stability. A method to more effectively screen for cocrystals
will be a powerful tool within the field of pharmaceutics. |
| Title
of Dissertation: |
“Cocrystals
Solubility and Solution Complexation to Develop Rational Cocrystal
Screening Methods.” |
| Degrees
Received: |
B.S., Pharmaceutical
Sciences, Drake University, May 2003 |
| Honors
Received: |
2006 AFPE
Pre-Doctoral Fellowship; 2004 NIH Pharmaceutical Sciences Training
Program (PSTP) Pre-Doctoral Training Fellow; 2003, Rackham Regents
Fellow, Magna Cum Laude-Drake University; 2003-99 Dean’s
and President’s List-Drake University |
| AFPE
Award: |
Abe Plough
Memorial AFPE Pre-Doctoral Fellowship in the Pharmaceutical Sciences |
HUU NGUYEN |
University
of Illinois at Chicago College of Pharmacy |
| Major
|
Pharmacognosy |
| GPA:
|
3.61/4.0 |
| Graduation
Date: |
February
2007 |
| Focus
of Research: |
To examine
the knowledge and practices of plant therapy among urban Vietnamese
and relate these beliefs and uses to modern medicine, with a specific
emphasis on investigating the potential anti-inflammatory activity
of food plants using the COX-2 inhibitory assay. |
| Title
of Dissertation: |
“The
Role of Traditional Botanical Beliefs and Health Practices Among
Urban Vietnamese Immigrants and Natives in Modern Medicine.” |
| Degrees
Received: |
B.S., Biochemistry,
North Carolina State University, May 2000
B.S., Botany, North Carolina State University, May 2000 |
| Honors
Received: |
2006 AFPE
Pre-Doctoral Fellowship; 2005, NIH Supplement Grant, EXPORT Grant
– NIH, Van Doren Scholar; 2002, Edward Benes Fund |
| AFPE
Award: |
Albert B.
Fisher, Jr. Citation AFPE Pre-Doctoral Fellowship in the Pharmaceutical
Sciences |
JUSTIN P. PENNINGTON |
University
of Kansas School of Pharmacy |
| Major
|
Medicinal/Pharmaceutical
Chemistry |
| GPA: |
3.66/4.00 |
| Graduation
Date: |
May 2007 |
| Focus
of Research: |
To develop
an isotopically labeled fluorescent tag for the analysis of protein
bound DOPA. The isotopic label contains a mass shift of ten units
that allows for relative quantitation of healthy versus diseased
samples. Once developed, the tag will be applied to various tissue
samples and used for proteomic analysis to identify sites of oxidation.
Protein bound DOPA has been linked to various age dependent pathologies
including arteriosclerosis. Proteomics research allows for greater
understanding of various diseases by identifying sites of post-translation
modifications that directly relate to an observed disease state. |
| Title
of Dissertation: |
“Development
of Novel Techniques for the Analysis of Protein Bound DOPA as
Indicators of Hydroxyl Radical-Mediated Modifications.” |
| Degrees
Received: |
M.S., Pharmaceutical
Chemistry, University of Kansas, May 2005
B.S., Math and Chemistry, Briar Cliff University, Sioux City IA,
May 2002 |
| Honors
Received: |
2006 AFPE
Pre-Doctoral Fellowship; 2002, Chemistry Student of the Year;
2001, Maytag Innovation Award for Student/Faculty; 1998, Presidential
Scholarship BCU; 1998, Doyle Leadership Award |
| AFPE
Award: |
Pfizer Inc.
- AFPE Pre-Doctoral Fellowship in the Pharmaceutical Sciences |
BRIANNA L. PETERSON |
University
of Georgia College of Pharmacy |
| Major
|
Pharmacology/Toxicology |
| GPA: |
4.0/4.0 |
| Graduation
Date: |
May 2007 |
| Focus
of Research: |
To determine
the role calcium-independent phospholipase A2 plays in neuronal
cell death
induced by drugs of abuse. This research utilizes a lipodomic
approach to examine the role
calcium-independent phospholipase A2 in oxidant-induced neural
cell death. |
| Title
of Dissertation: |
“Calcium-Independent
Phospholipase A2 Mediates Neuronal Cell Death During Oxidative
Stress Induced by Drugs of Abuse.” |
| Degrees
Received: |
M.S., Forensic
Science, University if Illinois at Chicago, August 1999
B.S., Chemistry, University of Wisconsin La Crosse, May 1997 |
| Honors
Received: |
2006-05 AFPE
Pre-Doctoral Fellowship; 2006, UGA Dissertation Completion Assistantship,
Society of Toxicology In-Vitro Section Award, UGA Interdisciplinary
Program in Toxicology Award; 2005 Society of Toxicology In-Vitro
Section Award; 2003, UGA University Wide Graduate Fellowship;
1997, Allen Chemistry Graduate Incentive; 1996, Golden Key Nation
Honor Society |
| AFPE
Award: |
Pfizer Inc.
- AFPE Pre-Doctoral Fellowship in the Pharmaceutical Sciences |
SUZANNE T. PHILLIPS |
Virginia
Commonwealth University School of Pharmacy |
| Major
|
Social &
Administrative Sciences |
| GPA:
|
3.76/4.0 |
| Graduation
Date: |
May 2008 |
| Focus
of Research: |
To undertake
a multi-center analysis that will assign a quantifiable cost to
antimicrobial resistance on an individual patient level that will
aid in clinical decision making. The development of antimicrobial
resistance is a growing concern and the pharmaceutical pipeline
appears relatively dry with respect to novel antibiotics. Therefore,
more prudent use needs to be exercised with currently available
therapies. When treating the individual patient, the benefit of
prescribing an antibiotic often outweighs any potential consequences
since their side effect profiles are reasonably mild. However,
with each antibiotic administration there is resistance consequence.
The consequence has previously been intangible, but this analysis
will assign tangible quantifiable cost to resistance on an individual
patient level. |
| Title
of Dissertation: |
“The
Cost of Antimicrobial Resistance.” |
| Degrees
Received: |
B.A., Chemistry,
Washington and Lee University, December 2001 |
| Honors
Received: |
2006 AFPE
Pre-Doctoral Fellowship; 2005-03, Dean’s List |
| AFPE
Award: |
National
Community Pharmacists Association - AFPE Pre-Doctoral Fellowship
in the Pharmaceutical Sciences |
JOANNE E. REILAND |
University
of Iowa College of Pharmacy |
| Major
|
Pharmaceutics |
| GPA:
|
3.90/4.00 |
| Graduation
Date: |
December
2007 |
| Focus
of Research: |
To develop
and validate an epithelial cell culture model of the mammary epithelium.
This in-vitro model will be used to examine the roles of various
epithelial transport proteins on drug transport across the mammary
epithelium. The research focuses on carrier-mediated drug transport
processes in the mammary epithelium. Improved understanding of
carrier-mediated processes will aid in the prediction of drug
concentration in breast milk. |
| Title
of Dissertation: |
“A
Cell Culture Model for Studying Mammary Drug Transport.” |
| Degrees
Received: |
B.S., Biochemistry,
University of Iowa, December 2002 |
| Honors
Received: |
2006, AFPE
Pre-Doctoral Fellowship; 2005, Keith Guillory Pharmaceutics Graduate
Fellowship; 2003, Presidential Graduate Fellowship; 2002, Honors
in Biochemistry, Graduation with Highest Distinction |
| AFPE
Award: |
Ernest Mario
Endowed AFPE Pre-Doctoral Fellowship in the Pharmaceutical Sciences
|
GARRETT R. RETTIG |
University
of Iowa College of Pharmacy |
| Major: |
Medicinal/Pharmaceutical
Chemistry |
| GPA: |
3.65/4.00 |
| Expected
Graduation: |
May 2007 |
| Focus
of Research: |
To develop
a short nuclear localizing peptide (NLP) containing a photo-labile
function to covalently label plasmid DNA in order to optimize
the nuclear localizing peptide to allow for improved uptake via
the nuclear pore complex. The peptide increases nuclear uptake
of the plasmid and allows for increased transgene expression.
The nuclear pore complex is responsible for mediating the uptake
of many cytosolic proteins. The NLP mimics the amino acid sequence
that allows a protein to enter the nucleus. Covalently labeling
plasmid DNA with the NLP should facilitate nuclear targeting and
increase transgene expression. |
| Title
of Dissertation: |
“Design
of Nuclear Localizing Peptides to Increase Gene Transfer Efficiency.” |
| Degrees
Received: |
B.A., Biology,
Wartburg College, May 2003 |
| Honors
Received: |
2006, AFPE
Pre-Doctoral Fellowship, NMCS Meeting Travel Grant; 2006-05, AFPE
Pre-Doctoral Fellowship, NIH Pharmacological Sciences Training
Grant; 2003, University of Iowa MNPC Fellowship |
| AFPE
Award: |
Ortho-McNeil
Janssen Scientific Affairs - AFPE Pre-Doctoral Fellowship
in the Pharmaceutical Sciences |
BRENT L. ROLLINS |
University
of Georgia College of Pharmacy |
| Major
|
Social &
Administrative Sciences |
| GPA:
|
3.88/4.00 |
| Graduation
Date: |
May 2008 |
| Focus
of Research: |
To study
how to maximize the time community pharmacists are able to spend
with patients on a day-to-day basis to allow the profession to
provide clinical services, such as medication therapy management
services (MTMS), in the community setting where the majority of
the prescriptions are filled. A patient satisfaction survey will
be utilized to measure if more time spent with patients directly
relates to patient satisfaction with pharmacy services. |
| Title
of Dissertation: |
“Pharmacists
and Time with Patients – Does it Matter and How To Maximize
It” |
| Degrees
Received: |
B.S., Pharmacy,
Ohio Northern University, May 2004 |
| Honors
Received: |
2006 AFPE
Pre-Doctoral Fellowship; 2004, Faculty Recognition Award-Graduating
Student; 2003, Louis Vottero Pharmacy Practice Research Award;
1999, Point Pleasant High School Valedictorian |
| AFPE
Award: |
Robert Lincoln
McNeil Memorial AFPE Pre-Doctoral Fellowship in the Pharmaceutical
Sciences |
ALEXANDRA J. SCHIEWE |
University
of Southern California School of Pharmacy |
| Major
|
Pharmaceutical
Sciences |
| GPA:
|
3.84/4.00 |
| Graduation
Date: |
May 2007 |
| Focus
of Research: |
To undertake
computational research in the area of structural prediction of
protein interactions and molecular dynamics of bimolecular structures
with the ultimate goal of developing novel pharmaceutical therapies
and vaccines for the treatment of autoimmune diseases. A general
model of major histocompatibility complex (MHC) peptide-T cell
receptor (TCR) recognition will be developed as part of this research.
The study of MCH-peptide interactions is important for the development
of new vaccines and therapies for infections diseases, autoimmune
diseases, and cancers. |
| Title
of Dissertation: |
“Conformational
Prediction of Major Histocompatibility Complex-Peptide-T Cell
Receptor (MHC-peptide-TCR) Binding Interactions.” |
| Degrees
Received: |
B.S., Pharmacological
Chemistry, University of California, San Diego, June 2001 |
| Honors
Received: |
2006-05,
AFPE Pre-Doctoral Fellowship, USC Graduate Teaching Fellowship |
| AFPE
Award: |
Teva Pharmaceuticals
- AFPE Pre-Doctoral Fellowship in the Pharmaceutical Sciences |
JOSHUA J. SCHMIDT |
University
of Wisconsin – Madison School of Pharmacy |
| Major: |
Pharmaceutical
Sciences |
| GPA: |
3.74/4.00 |
| Expected
Graduation: |
May 2007 |
| Focus
of Research: |
To carry
out comparative peptidomics using mass spectrometry, immunohistochemistry,
and physiological studies, to spatially profile and image peptides
using mass spectrometry (MS) in the crustacean nervous system,
and to identify markers of prion disease in the cerebrospinal
fluid (CSF) and/or serum for the development of an ante-niomen
diagnostic tool. |
| Title
of Dissertation: |
“Comprehensive
Characterization of Chemical Signaling Molecules in Complex Biological
Systems: I. A Comparative Neuropeptidomic Study of Crustacean
Nervous Systems II. Spatial Profiling and Imaging of Peptides
in the Crustacean Nervous System III. Discovery of Prion Disease
Markers in Cerebral Spinal Fluid (CSF) and Serum.” |
| Degrees
Received: |
B.S., Biochemistry,
Bethel College, May 2002
B.S., Biology, Bethel College, May 2002
B.A., Chemistry, Bethel College, May 2002 |
| Honors
Received: |
2006-04,
AFPE Pre-Doctoral Fellowship; 2003, WI Distinguished Fellow-Wakefield
Fellowship; 2002, WI Distinguished Fellow-Perlmann Fellowship;
2001, Bethel College Chemistry Scholarship; 2000, Academic Scholarship-Bethel
College; 1998, Academic Scholarship-St. Mary’s University |
| AFPE
Award: |
PhRMA Foundation
- AFPE Pre-Doctoral Fellowship in the Pharmaceutical Sciences |
MATTHEW D. SCHMIDT |
University
of Iowa College of Pharmacy |
| Major
|
Medicinal/Pharmaceutical
Chemistry |
| GPA:
|
3.63/4.00 |
| Graduation
Date: |
August 2009 |
| Focus
of Research: |
To develop
novel analgesics and drug abuse therapeutics. Although morphine
and its derivatives play a key role in modern medicine, they suffer
from serious side effects that include tolerance, dependence,
and respiratory depression. Novel analgesics are needed with fewer
or less severe side effects. Through natural product isolation
and synthetic efforts in target drug design, it is possible to
apply medicinal chemistry and pharmacology to understand the biological
interactions of these compounds and to develop new potential therapeutics
with enhanced activity and minimal undesirable effects. At this
time, there is a limited number of FDA approved treatments for
drug abuse and they are only available for a few drugs. Of the
treatments available, few are very effective. Even though several
treatments are approved for nicotine addiction, smoking continues
to be the greatest cause of preventable death in the United States,
with one in five deaths attributed to smoking. Clearly, new therapeutics
are necessary to properly address this widespread epidemic. Consequently,
part of our research centers around the development of new compounds
with altered levels of tolerance and dependence, which, in addition
to being desirable therapeutics, could be potential treatments
for drug abuse. |
| Title
of Dissertation: |
“Isolation,
Synthesis and Pharmacological Evaluation of Novel Nicotine Acetylcholinc
Receptor Ligands Based on Gedunin, a Litninoid Found in Azadirachta
Indica.” |
| Degrees
Received: |
B.S., Chemistry
ACS Certified with Polymer Emphasis, Biology, Pre.Pharmacy, Minor
in Natural Resource Management, University of Wisconsin-Stevens
Point, May 2004 |
| Honors
Received: |
2006, AFPE
Pre-Doctoral Fellowship, National Medicinal Chemistry Symposium
Travel Award; 2006-05, Chancellor’s List; 2005, Center for
Biocatalysis and Bioprocessing Predoctoral Fellowship; 2004, Jay
Reed Memorial Conservation Scholarship; 2003, UW-Stevens Point
Student Research Fund Grant, University Leadership Award, Arthur
W. Mueller, Jr. Natural Resources Scholarship, Wisconsin Traditional
Archers Scholarship; 2002, Wisconsin Bowhunters Association Scholarship,
Pucci Family Biology Scholarship, Martha W. Sorenson Research
Award; 2002-98, Dean’s List, Business Products Industry
Association Award; 2001, Doug Stephens Memorial Student Research
Award |
| AFPE
Award: |
United States
Pharmacopeia (USP) – AFPE Pre-Doctoral Fellowship in the
Pharmaceutical Sciences |
JIE J. SHENG |
University
of Michigan College of Pharmacy |
| Major
|
Pharmaceutics |
| GPA:
|
3.95/4.00 |
| Graduation
Date: |
September
2007 |
| Focus
of Research: |
To build
theoretical models to estimate the intrinsic drug flux in various
buffers, particularly in bicarbonates and phosphates, to measure
the corresponding dissolution of poorly soluble drugs experimentally,
and to gain mechanistic understanding of buffer effects on drug
dissolution by comparing the experimental results with the theory.
The research will study the buffer effects of dissolution of BCSII
drugs with the goal of improving the accuracy of predicting drug
absorption of a NCE, thus reducing cost and facilitating drug
development . |
| Title
of Dissertation: |
“In-Vitro
Dissolution of Poorly Soluble Drugs.” |
| Degrees
Received: |
M.S., Pharmaceutics,
University of Minnesota, December 1998
B.S., Pharmacy, Beijing University, June 1992 |
| Honors
Received: |
2006-05,
AFPE Pre-Doctoral Fellowship |
| AFPE
Award: |
Generic Pharmaceutical
Association - AFPE Pre-Doctoral Fellowship in the Pharmaceutical
Sciences |
MATTHEW G. SLATTERY |
University
of Wisconsin-Madison School of Pharmacy |
| Major:
|
Pharmaceutical
Sciences |
| GPA:
|
3.93/4.00 |
| Graduation
Date: |
August 2007 |
| Focus
of Research: |
To understand
the mechanisms by which eukaryotic cells leave a quiescent state,
with particular emphasis on the transcriptional induction of genes
necessary for cellular growth and cell division and to learn about
novel pathways for glucose sensing, an incompletely understood
process that is of medicinal important in humans. A vast majority
of the cells in our body exist in a quiescent state, and the process
by which cells leave this state is important for normal development,
immune system function, and cancer. The goal is to use a model
organism, Saccharomyces cerevisiae, to explore signaling pathways
that are conserved in higher eukaryotes such as humans in order
to refine our knowledge of growth signaling and to identify potential
drug targets. |
| Title
of Dissertation: |
“Glucose
Signaling and Cell Proliferation in Saccharomyces Cerevisiae.” |
| Degrees
Received: |
B.S., Pharmacology
and Toxicology, University of Wisconsin-Madison, May 2001 |
| Honors
Received: |
2006-05,
AFPE Pre-Doctoral Fellowship; 2004, UW School of Pharmacy Travel
Grant; 2001, Covance Laboratories Award; 1997, College of Agriculture
& Life Sciences Ferdinand Plaenert Award, Wisconsin Academic
Excellence Scholarship |
| AFPE
Award: |
AFPE 21st
Century Club Alumni & Friends Pre-Doctoral Fellowship in the
Pharmaceutical Sciences |
MARCUS M. STAVCHANSKY |
University
of Texas at Austin College of Pharmacy |
| Major
|
Social and
Administrative Sciences |
| GPA:
|
3.75/4.00 |
| Graduation
Date: |
May 2007 |
| Focus
of Research: |
To observe
and analyze physician prescribing behavior at the point of care
using an electronic clinical decision support system. |
| Title
of Dissertation: |
“Utilization
of ‘Point of Care’ and Clinical Decision Support Software:
an Analysis of Physician Prescribing Behavior.” |
| Degrees
Received: |
Pharm.D.,
University of Texas at Austin, May 2003 |
| Honors
Received: |
2006 AFPE
Pre-Doctoral Fellowship; 2003-01, J&J Fellowship and Endowments;
2001-97, H.E.B. Pharmacy Scholarship; 2000, Elected President
of Pharm.D. class; 1996, Dean’s List; 1996-94, Texas Achievement
Award |
| AFPE
Award: |
AFPE 21st
Century Club Alumni & Friends Pre-Doctoral Fellowship in the
Pharmaceutical Sciences |
JOE W. SU |
University
of Wisconsin- Madison School of Pharmacy |
| Major
|
Pharmaceutical
Sciences |
| GPA:
|
3.92/4.00 |
| Graduation
Date: |
July 2008 |
| Focus
of Research: |
To use a
novel methodology for the elucidation of molecular details in
dynamic drug systems in order to reduce complex binding phenomena
to simple underlying mechanisms, which may be accurately assessed
by computational and spectroscopic methods. By synergistically
integrating ever-evolving computational and spectroscopic technologies
to our model host-guest binding studies, we aim to gain broader
chemical insights into host-guest drug delivery problems. |
| Title
of Dissertation: |
“Investigation
of 222 Cryptate Binding by Computational and Spectroscopic Methods.” |
| Degrees
Received: |
B.S., Chemistry,
University of California at Berkeley, May 2002 |
| Honors
Received: |
2006-04,
AFPE Pre-Doctoral Fellowship, Oscar Rennebohm Outstanding Teaching
Award; 2002, Wisconsin Distinguished Fellow; 2000, Golden Key
National Honor Society |
| AFPE
Award: |
Josiah Kirby
Lilly, Sr. Memorial AFPE Pre-Doctoral Fellowship in the Pharmaceutical
|
KEVIN J. TIDGEWELL |
University
of Iowa College of Pharmacy |
| Major
|
Medicinal/Pharmaceutical
Chemistry |
| GPA:
|
3.80/4.00 |
| Graduation
Date: |
August 2008 |
| Focus
of Research: |
To isolate
salvinorin A from the dried leaves of Salvia divinorum and to
convert salvinorin A into a wide range of derivatives through
synthetic methodologies. By systematically modifying salvinorin
A, we will seek better understanding of the required pharmacophore
for affinity and activity at opioid receptors. Compounds which
show promise (i.e. high selectivity and affinity) will be tested
in in-vivo pharmacological tests of nociception and drug self-administration.
Compounds that have proven to show antinociceptive properties
will be tested in chronic dosing assays to look at their potential
for the development of tolerance. |
| Title
of Dissertation: |
“Design,
Synthesis and Evaluation of Novel Mu Opioid Ligands Based on the
Neoclerodane Diterpene Salvinorin A.” |
| Degrees
Received: |
B.S., Chemistry,
Minor in Mathematics, Mereyhurst College, May 2003 |
| Honors
Received: |
2006-05,
AFPE Pre-Doctoral Fellowship, INRC Travel Award, Pharmacy Graduate
Program Excellence Award; 2004, Pharmacological Sciences Training
Grant, ACS Medical Chemistry Travel Grant; 2003, MNPC Fellowship,
Mercyhurst College President’s Award for Natural Sciences;
2003-99, Dean’s List-Mercyhurst College |
| AFPE
Award: |
AFPE 21st
Century Club Alumni & Friends Pre-Doctoral Fellowship in the
Pharmaceutical Sciences |
ADAM L. VanWERT |
Medical
University of South Carolina College of Pharmacy |
| Major
|
Pharmacology/Toxicology |
| GPA:
|
3.92/4.0 |
| Graduation
Date: |
May 2008 |
| Focus
of Research: |
To determine
the in-vivo consequences of deletion of organic anion transporter
3 (Oat3) in a knockout mouse model by determining the impact of
Oat3 knockout on elimination and distribution of pharmacotherapeutic
and endogenous substrates. This transporter is a candidate for
contributing to the classical pathway of organic anion secretion
in the renal proximal tubule and therefore may play a role in
detoxification/elimination of organic anion substrates. Organic
anion transporters play a pivotal role in absorption, distribution,
and excretion as a result of their positioning in barrier epithelia
of numerous organs. |
| Title
of Dissertation: |
“In-Vivo
Implications of Organic Anion Transporter 3 Knockout.” |
| Degrees
Received: |
Pharm.D.,
Wilkes University Nesbitt School of Pharmacy, May 2003 |
| Honors
Received: |
2006, AFPE
Predoctoral Fellowship; 2006-05, Chancellor’s List; 2003,
TEVA Certificate of Achievement in Pharmacy, Graduated Summa Cum
Laude; 2002-01, National Dean’s List; 2001-97, Presidential
Scholarship |
| AFPE
Award: |
United States
Pharmacopeia (USP) - AFPE Pre-Doctoral Fellowship in the Pharmaceutical
Sciences |
DEEPALI VARTAK |
University
of Illinois at Chicago College of Pharmacy |
| Major
|
Pharmaceutical
Sciences |
| GPA:
|
4.0/4.0 |
| Graduation
Date: |
May 2007 |
| Focus
of Research: |
To develop
a targeted drug delivery strategy for treatment of ocular diseases
characterized by neovascularization. A polymeric drug delivery
system incorporating a peptide substrate to control the release
of anti-angiogenic drug in the presence of angiogenic matrix metalloprolenses
will be developed and subjected to physiochemical and biological
characterization. Though aimed at ocular angiogenesis, the proof
of concept can be extended to target tumor angiogenesis. |
| Title
of Dissertation: |
“Targeted
Drug Delivery for Ocular Anti-Angiogenesis.” |
| Degrees
Received: |
M.S., Pharmaceutics,
Duquesne University, May 2001
M. Pharm. Science, University of Mumbai, India, December 1997
B. Pharm. Science, University of Mumbai, India, December 1995 |
| Honors
Received: |
2006, AFPE
Pre-Doctoral Fellowship, Van Doren Scholar Award, University Fellowship;
2005, AAPS-PDD Section travel award for poster presentation at
2005 AAPS meeting |
| AFPE
Award: |
GlaxoSmithKline
- AFPE Pre-Doctoral Fellowship in the Pharmaceutical Sciences |
CLIFFORD J. WHATCOTT |
University
of Arizona College of Pharmacy |
| Major
|
Medicinal/Pharmaceutical
Chemistry |
| GPA:
|
3.89/4.00 |
| Graduation
Date: |
August 2007 |
| Focus
of Research: |
To study
the role of poly(ADP-ribosyl)ation in the cellular response to
DNA damage and the mechanism that poly(ADP-ribose) polymerase
as well as its synthetic product poly(ADP-ribose) may serve in
eliciting a cell death response. The research will focus on the
effect of interactions with mitochondria with the goal of discovering
new proteins or interactions where inhibition may prove therapeutic
in the treatment of cancer or other diseases. |
| Title
of Dissertation: |
“The
Role of Poly (ADP-ribosyl) ation in Cell Death.” |
| Degrees
Received: |
B.S., Microbiology,
Brigham Young University, August 2003 |
| Honors
Received: |
2006-05 AFPE
Pre-Doctoral Fellowship, 2006-05, Caldwell Health Sciences Research
Fellow; 2005-04, Yuma Friends AHSC Young Investigators Award;
2004, Appointed to Dean’s Research Affairs Committee; 2003-00,
Avnet Collegiate Honors Scholarship; 2002-01, Joe and Joanne Livingston
Scholarship; 2002-96, Robert C. Byrd Honors Scholarship, Brigham
Young University Scholarship; 1997-96, American Legion Auxiliary
#26 Scholarship |
| AFPE
Award: |
Novartis
Pharmaceuticals - AFPE Pre-Doctoral Fellowship in the Pharmaceutical
Sciences |
JOHN S. YANUSAS |
University
of Rhode Island College of Pharmacy |
| Major
|
Pharmaceutics |
| GPA:
|
3.8/4.0 |
| Graduation
Date: |
January 2008 |
| Focus
of Research: |
To develop
an understanding of peptide biopharmaceutical kinetics and the
mechanism of delivery of biopharmaceutical drugs by parenteral,
nasal, and pulmonary routes. Of particular interest is the use
and modification of natural polymers as they apply to the nasal
delivery technology when incorporating novel approaches to formulations.
It is believed that the use of natural polymers (polysaccrides)
in pharmaceutical formulations will eliminate or reduce the dose
of subcutaneous daily injections or decrease the frequency of
subcutaneous administration while increasing the use of other
non-invasive routes. |
| Title
of Dissertation: |
“An
Investigation of a Model Peptide API in Combination with a Novel
Natural Polymer (Polysialic acid) and other Permeation Enhancers/Mucoadhesives
in the Modulation of Nasal Tight Junctions for Nasal Delivery.” |
| Degrees
Received: |
MBA, Business,
University of Rhode Island, December 2003
B.S., Chemistry/Chemical Engineer, University of Connecticut,
December 1986 |
| Honors
Received: |
2006, AFPE
Pre-Doctoral Fellowship; 2004, Beta Gamma Sigma |
| AFPE
Award: |
Teva Pharmaceuticals
- AFPE Pre-Doctoral Fellowship in the Pharmaceutical Sciences |
